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Fofana, Bourlaye, Ph.D.

Chercheur scientifique, Biologie et physiologie moléculaire des plantes

Coordonnées :

440, avenue University
Charlottetown, Île-du-Prince-Édouard C1A 4N6
Téléphone : 902-370-1454
Télécopieur : 902-566-7468
Courriel : bourlaye.fofana@agr.gc.ca

Domaines d'expertise :

  • Biologie moléculaire des plantes
  • Physiologie moléculaire et biochimie des plantes
  • Voies métaboliques des plantes
  • Métabolites primaires et secondaires végétales 
  • Génomique du lin - qualité des graines - régulation des métabolites bioactifs
  • Génomique fonctionnelle du développement des graines 
  • Génomique fonctionnelle du développement des graines
  • Composés bioactifs végétaux - synthèse - régulation - altération
  • Génomique fonctionnelle - interactions plante-pathogène - éliciteurs - voies métaboliques
  • Profilage de l'expression génique et protéique à l'aide d'outils de bio-puce (microarray) et de protéomique
  • Marqueurs moléculaires - cartographie des loci à caractère quantitatif (QTL) - germoplasme - bioprospection
  • Lin 
  • Blé
  • Concombre
  • Églantier sauvage

Projets en cours :

  • Développement de carte génotype x metabolite de l'églantier sauvage aux fins de bioanalyses des maladies chroniques
  • Développement de ressources génomiques pour l'églantier sauvage
  • Génomique du lin : glycosylation de lignane, sa biodisponibilité et bioactivité
  • Développement d'une approche pour accroître la capacité antioxydante des produits de grandes cultures
  • Corroboration d'allégations santé relatives au lin

Affiliations :

  • Société canadienne de physiologie végétale
  • Groupe d'utilisateurs de SAS
  • Institut des agronomes de l'Iles du Prince Edouard (PEIIA)
  • Professeur auxiliaire, University of Prince Edward Island (UPEI)

Publications de recherche

2019

  • https://pag.confex.com/pag/xxvii/meetingapp.cgi/Session/5691

2018

  • https://pag.confex.com/pag/xxvi/meetingapp.cgi/Paper/30375
  • https://pag.confex.com/pag/xxvi/meetingapp.cgi/Paper/30386
  • https://www.eventscribe.com/2018/ASPB/searchbyposterbucket.asp?pfp=PosterBucket

2015

2014

2013

2012

  • Rasul, G., Humphreys, D.G., Wu, J., Brûlé-Babel, A.L., Fofana, B., et Glover, K.D. (2012). « Evaluation of preharvest sprouting traits in a collection of spring wheat germplasm using genotype and genotype x environment interaction model. », Plant Breeding, 131(2), p. 244-251. doi : 10.1111/j.1439-0523.2011.01931.x

2011

2010

2009

Autres publications relatives à la science

2019

  • Cultivated potato (Solanum tuberosum L.) is the third most consumed food crop after rice and wheat. Potato is an auto tetraploid crop species having a highly heterozygous genetic base and a complex genome making its genetic studies tedious. Recently, diploid potato breeding has regained interest in the potato genetics community. Genetically, diploid potatoes are easy to work with and can be used in the cultivated potato breeding process as genetic resources and also they can be grown on their own as varieties. However, diploid breeding continuum faces many challenges including anti-nutritional factors and self-incompatibilities. Whereas conventional breeding strategies contributed to the releasing of varieties with low SGA, substantial resources are still required to minimizing these anti-nutritional factors. Recently, we developed and characterized an ethyl methane sulfonate mutagenized pre-breeding diploid potato population for identifying lines with low anti-nutritional factors. The data will be presented and discussed in relation to the high potential for diploid potatoes as a complement to tetraploid potatoes and in pre-and post-harvest management contexts.

2017

  • Cloutier S, Ghose K, Somalraju A, McCallum J, Fofana B (2017) Further evidence that mutations in UGT74S1 alter SDG lignan glucoside profiles in EMS flax mutant lines. Proc 25th Plant and Animal Genome meeting, San Diego, CA, 14-18 Jan, P232

2016

  • Bizimungu, B., B Fofana, D. Main, J. McCallum, L. Kawchuk, and H. Tai. (2016) Development and characterization of diploid potato lines with agronomic and processing traits. “Breeding”, 100th Annual Meeting of The Potato Association of America, July 31- August 4, 2016, Amway Grand Plaza Hotel, Grand Rapids, Michigan, USA. (Presentation) http://potatoassociation.org/
  • Fofana, B., Ghose, K., McCallum, J.L., Somalraju, A., Cloutier, S., Deyholos, M.K., et Rowland, G.G. (2016). « Developing EMS flax mutant lines with altered SDG lignan glucosides. », PAGXXIV 2016, San Diego, USA, January 9-13, 2016.
  • Fofana, B., Ghose, K., McCallum, J.L., Somalraju, A., Cloutier, S., Deyholos, M.K., et Rowland, G.G. (2016). « Developing EMS flax mutant lines with altered SDG lignan glucosides. », PAGXXIV, San Diego, USA, January 9-13, 2015. (Affiche)

2015

  • Alkhnajari, A., Ghose, K., Somalraju, A., Samis, K., et Fofana, B. (2015). « Metagenomics of the buckwheat rhizophere's microbial diversity in wireworm-infested and non-infested soils. », UPEI Graduate Day, UPEI, MacDougall Hall, May 2015.
  • Alkhnajari, A., Somalraju, A., Ghose, K., Samis, K., et Fofana, B. (2015). « Microbial diversity of buckwheat rhizosphere in wireworm-infested and non-infested soils using metagenomics. », UPEI Multidisciplinary Graduate Research Conference, UPEI, MacDougall Hall, August 6-8, 2015. (Affiche)
  • Fofana, B., Ghose, K., McCallum, J.L., You, F.M., et Cloutier, S. (2015). « UGT74S1 is a single-copy gene and is unique In controlling Secoisolariciresinol Diglucoside (SDG) formation in flax. », Botany 2015 Joint Conference: Science and plants for people, Shaw Convention Center, Edmonton, Alberta, Canada, July 25-30, 2015. (Affiche)
  • Fofana, B., Ghose, K., You, F.M., et Cloutier, S. (2015). « UGT74S1 Is Unique In Controlling Secoisolariciresinol Diglucoside (SDG) Formation In Flax. », XXIII Plant and Animal Genome Conference, San Diego, CA, USA, January 10-14, 2015, p. 160. (Résumé)
  • McCallum, J.L., Mills, A.A.S., Fofana, B., et Kirby, C.W. (2015). « Hops Germplasm Improvement. », 2015 AAFC Charlottetown Stakeholder Day, Harrington, PEI, Canada, July 14, 2015. (Affiche)
  • Somalraju, A., Alkhnajari, A., Ghose, K., Main, D., et Fofana, B. (2015). « Characterizing EMS-Mutagenized pre-breeding potato lines using NGS and Phenotyping. », UPEI Graduate Day, UPEI, MacDougall Hall, May 2015. (Affiche)
  • Somalraju, A., Alkhnajari, A., Ghose, K., Main, D., et Fofana, B. (2015). « Use of NGS and Phenotyping for Developing EMS-Mutagenized Pre-breeding Potato lines Potentially Low In Anti-nutritional Factors. », Botany 2015 Joint Conference: Science and plants for people, Shaw Convention Center, Edmonton, Alberta, Canada, July 25-30, 2015. (Affiche)

2014

  • Cloutier, S., Rowland, G.G., Booker, H.M., Deyholos, M.K., Datla, R.S.S., Duguid, S.D., Fofana, B., Reaney, M.J.T., Selvaraj, G., Smyth, S., Wang, E., Weselake, R.J., You, F.M., Zou, J.W., et Barker, C. (2014). « The TUFGEN project. », 65th Flax Institute, Fargo, North Dakota, USA, March 27-28, 2014, Oral presentation, p. 39-48.
  • Fofana, B. (2014). « How gene discovery meets plant and bioreactor genetic resources development? », UPEI – Department of Biology seminar series, Biology Department, Charlottetown, Canada, October 10, 2014. (Présentation)
  • Fofana, B. (2014). « So, what we do in Fofana’s bioproducts and Bio-processes lab? », CBH seminar series, NRC building, Charlottetown, Canada, April 10, 2014. (Présentation)
  • Fofana, B. (2014). « Stopping potato greening: A cure may be in the works for sunburned potatoes – which is music to the industry’s ears. », Spud Smart, 11(2), p. 22-26.
  • Fofana, B. (2014). Breeding out glycoalkaloids: A Canadian project employs new genetic tools to speed up potato breeding. AG Annex, Reported by Treena Hein, March 2014. (Rapport)
  • Fofana, B. et Sanderson, K.R. (2014). « AAC Sylvia-Arlene. », Plant Varieties Journal, 93.
  • Fofana, B., Ghose, K., McCallum, J.L., et Cloutier, S. (2014). « Flax SDG lignan glucosylation: from gene discovery to flax lines with altered SDG profiles. », Plant Biology 2014, Portland, Oregon, USA, July 12-16, 2014. (Affiche)
  • Somalraju, A., Ghose, K., Carter, L., Samis, K., et Fofana, B. (2014). « Phenotypic characterization of an EMS-Mutagenized Dihaploid Potato Population. », Science Graduate Studies Day, Charlottetown, PE, Canada, May 2, 2014. (Présentation)
  • Somalraju, A., Ghose, K., McCallum, J.L., et Fofana, B. (2014). « Une patate sans composés toxiques? », CLRC open House, Charlottetown, Canada, August 23, 2014. (Présentation)
  • Wang, Y., Fofana, B., Roy, M., et Ghose, K. (2014). « Flaxseed lignan secoisolariciresinol diglucoside improves insulin sensitivity through upregulating GLUT4 expression in diet-induced obese mice. », FASEB Meeting 2014, San Diego, USA, April 26-30, 2014, Supplement, Vol. 28 No.1 Supplement 829.25.

2013

  • Fofana, B. (2013). « Lignan biosynthesis, bioactivity and bioavailability. », Genome Canada flax Tufgen project final AGM presentation, Saskatoon, Canada, November 28-29, 2013. (Présentation)
  • Fofana, B., Ghose, K., Chapman, R.G., et Sanderson, K.R. (2013). « Genetic, Agronomy, and Metabolomics of Prince Edwards Island Wild Rose Collection and Promise for Cultivar Development. », dans Kulka, M. (dir.) - Using Old Solutions to New Problems - Natural Drug Discovery in the 21st Century, InTech, Open Access Publisher, Chapitre 2, p. 37-62.
  • Ghose, K., McCallum, J.L., Stetson, C., et Fofana, B. (2013). « Réduire les facteurs antinutritionnels des pommes de terre. », Open House (Poster), Harington, PE, Canada, August 16, 2013. (Présentation)
  • Ghose, K., Selvaraj, K., McCallum, J.L., Datla, R.S.S., Cloutier, S., et Fofana, B. (2013). « Key Catalytic Amino Acids for a Flax Secoisolariciresinol Glycosyltransferase as determined by Molecular Modeling and Site-Directed Mutagenesis. », 2013 CSPB/SCBV Annual General Meeting, Laval University, Quebec City, Canada, June 25-28, 2013.
  • Wang, Y., Fofana, B., et Roy, M. (2013). « Anti-Diabetic Potential of Flaxseed Lignan Secoisolariciresinol Diglucoside in Diet-Induced Obese Mice. », FASEB 2013 April Meeting, Supplement ;27:lb377. (Résumé)

2012

  • Fofana, B. (2012). « An easy way for the biofortification of field crops antioxidant capacity by increasing selenoprotein content: consequences to human health. », University of Prince Edward Island (UPEI), Biology Department Seminar Series, Duffy Science Centre, Charlottetown, PEI, Canada, January 13, 2012. (Présentation)
  • Fofana, B. et Selvaraj, K. (2012). « An Overview of Plant Photosynthesis Modulation by Pathogen Attacks. », dans Najafpour, M.M. (dir.) - Advances in Photosynthesis - Fundamental Aspects, InTech, Open Access Publisher, Chapitre 22, p. 465-486.
  • Power, K.A., Villeneuve, S., Mondor, M., Fustier, P., Arcand, Y., Lamarche, F., Britten, M., Cui, S.W., Tsao, R., Fofana, B., et Wanasundara, J.P.D. (2012). « Recent progress on the incorporation of flaxseed into cereal based matrices: delivery of bioactives to target sites and a comprehensive assessment of their biological effects. », 64th Flax Institute of the United States, Doublewood Inn, Fargo, ND, USA, March 29-30, 2012. (Présentation)

2011

  • Fofana, B., Main, D., Ghose, K., Grimmett, M.G., Kirby, C.W., McCallum, J.L., Peters, R.D., Drake, K.A., Locke, S.J, et Sweeney, M.E. (2011). « Improving the antioxidant capacity of field crops by increasing selenoprotein content. », 2011 Annual Meeting of the Canadian Phytopathological Society (with Plant Canada 2011), Halifax, NS, Canada, July 17-21, 2011, pp. 61, #1145. (Présentation)
  • Ghose, K., Sanderson, K.R., Kirby, C.W., McCallum, J.L., et Fofana, B. (2011). « Genetic structure of Prince Edwards island wild rosehip ecotypes as revealed by single nucleotide polymorphism. », Canadian Phytopathological Society (CPS) 82nd Annual Meeting (with Plant Canada 2011), Halifax, NS, Canada, July 17-21, 2011, CSHS-9, p. 283. (Affiche)
  • Kirby, C.W., McCallum, J.L., Bernard, K., et Fofana, B. (2011). « Cooked Flax Bolls: An Alternative Omega-3 Fatty Acid Source. », MOOT XXIV NMR Minisymposium, Toronto, ON, Canada, October 21-22, 2011. (Affiche)
  • Selvaraj, K., Ghose, K., Nixon, M., Cloutier, S., et Fofana, B. (2011). « Molecular and functional characterization of flax SDG lignan glycosyltransferases. », Canadian Society of Plant Physiologists Eastern Regional Meeting & Plant Development Workshop / Congrès de la Société Canadienne de Physiologie Végétale & Congrès de Développement Végétale (Congrès Régional de l’Est), Carleton University, Ottawa, ON, Canada, December 2-3, 2011, P22, p. 40.

2010

  • Cloutier, S., Cloutier, S., Rowland, G.G., Datla, R.S.S., Deyholos, M.K., Duguid, S.D., Fofana, B., Reaney, M.J.T., Selvaraj, G., Smyth, S., Wang, E., Weselake, R.J., Zou, J., et Barker, C. (2010). « Total Utilization Flax Genomics (TUFGEN): A Genome Canada Project. », Plant & Animal Genome XVIII Conference, Town & Country Convention Center, San Diego, CA, USA, January 9-13, 2010, P018. (Affiche)
  • Fofana, B., Ragupathy, R., et Cloutier, S. (2010). « Flax Lipids: Classes, biosynthesis, genetics and the promise of applied genomics for understanding and altering of fatty acids. », dans Gilmore, P.L. (dir.) - Lipids: Categories, Biological Functions and Metabolism, Nutrition, and Health, Nova Science Publishers Inc, Chapitre 3, p. 71-98.
  • Ghose, K., McCallum, J.L., Kirby, C.W., Sanderson, K.R., et Fofana, B. (2010). « Genetic and matebolite diversity in Atlantic Canada wild roses and its implication in drug and cultivar development. », 2nd Maritime Natural Products Conference, Charlottetown, PEI, Canada, August 31-September 2, 2010.
  • Ghose, K., McCallum, J.L., Kirby, C.W., Sanderson, K.R., et Fofana, B. (2010). « Genetic and metabolite diversity in Atlantic Canada wild roses and its implications in drug and cultivar development. », Plant Biology 2010: Joint meeting of the Canadian Society of Plant Physiologists (CSPP) and American Society of Plant Biologists (ASPB), Montréal Convention Centre, Montréal, QC, Canada, July 31-August 4, 2010, P09073. (Affiche)
  • Johnson, J.B., Kulka, M., Wang, Y., Zidichouski, J., Saleh, T., Fofana, B., Kirby, C.W., McCallum, J.L., Sanderson, K.R., Berrue, F., Kerr, R., Mackinnon, S., Zhang, J., et Chapman, R.A. (2010). « Comparative evaluation of the immunomodulatory activities of selected Prince Edward Island rose hip varieties. », 10th Agricultural Biotechnology International Conference (ABIC), Saskatoon, SK, Canada, September 12-15, 2010. (Affiche)
  • Ragupathy, R., Cloutier, S., Rowland, G.G., Duguid, S.D., Datla, R.S.S., Selvaraj, G., Deyholos, M.K., Wang, E., Fofana, B., Zou, J., Reaney, M.J.T., Weselake, R.J., Philips, P., Smyth, S., et Barker, C. (2010 Internal). « Total utilization of flax genomics (TUFGEN). », Internal Review Meeting, Department of Biotechnology (DBT-Government of India) supported flaxproject, National Chemical Laboratory (NCL), Pune, India, June 16, 2010. (Présentation)
  • Selvaraj, K., Ghose, K., et Fofana, B. (2010). « Cloning and characterization of flax lignan biosynthesis and glycosylation genes. », 2nd Maritime Natural Products Conference, Charlottetown, PEI, Canada, August 31-September 2, 2010. (Présentation)

2009

  • Kirby, C.W., Bain, A., Hartman, J.S., Berno, B., Hazendonk, P., Ye, E., Zwanzinger, J., McCallum, J.L., et Fofana, B. (2009). « From Semi-Conductors to Fatty Acids – the Versatility of NMR. », 4th Annual Nuclear Magnetic Resonance Research Resource Workshop, Halifax, NS, Canada, November 14, 2009, Invited talk.
  • Kirby, C.W., McCallum, J.L., et Fofana, B. (2009). « NMR Studies of the Fatty Acids Present in Flax Seed Development. », MOOT XXII NMR Minisymposium, Carleton University, Ottawa, ON, Canada, October 17-18, 2009, 16. (Affiche)
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