Harris, Linda, Ph.D.

This page contains a list of publications. A full profile of this scientist is available at Linda J. Harris

Research publications

2018

Bahadoor, A., Brauer, E.K., Bosnich, W., Schneiderman, D., Johnston, A., Aubin, Y., Blackwell, B., Melanson, J.E., Harris, L.J. (2018). Gramillin A and B: Cyclic Lipopeptides Identified as the Nonribosomal Biosynthetic Products of Fusarium graminearum, 140(48), 16783-16791. http://dx.doi.org/10.1021/jacs.8b10017
Kebede, A.Z., Johnston, A., Schneiderman, D., Bosnich, W., Harris, L.J. (2018). Transcriptome profiling of two maize inbreds with distinct responses to Gibberella ear rot disease to identify candidate resistance genes, 19(1), http://dx.doi.org/10.1186/s12864-018-4513-4

2017

Luo, K., DesRoches, C.-L., Johnston, A., Harris, L., Zhao, H.-Y., Ouellet, T. 2017. Multiple metabolic pathways for metabolism of L-tryptophan in Fusarium graminearum. Can. J. Microbiol. 63: 921-927. DOI 10.1139/cjm-2017-0383.
Vachon, F., Overy, D.P., Hermans, A., Johnston, A., Sproule, A., Xue, A., Harris, L.J. Fusarium poae and emerging mycotoxins associated with fusarium head blight in Canada. Proceedings of 2017 Canadian Phytopathological Society – Eastern Ontario Regional Meeting, Ottawa, ON, Can. J. Plant Pathol. 40:3, 469.

2016

Bahadoor, A., Schneiderman, D., Gemmill, L., Bosnich, W., Blackwell, B., Melanson, J.E., McRae, G., Harris, L.J. (2016). Hydroxylation of Longiborneol by a Clm2-Encoded CYP450 Monooxygenase to Produce Culmorin in Fusarium graminearum, 79(1), 81-88. http://dx.doi.org/10.1021/acs.jnatprod.5b00676
Gunter, A.B., Hermans, A., Bosnich, W., Johnson, D.A., Harris, L.J., Gleddie, S. (2016). Protein engineering of Saccharomyces cerevisiae transporter Pdr5p identifies key residues that impact Fusarium mycotoxin export and resistance to inhibition, 5(6), 979-991. http://dx.doi.org/10.1002/mbo3.381
Harris, L.J., Balcerzak, M., Johnston, A., Schneiderman, D., Ouellet, T. (2016). Host-preferential Fusarium graminearum gene expression during infection of wheat, barley, and maize, 120(1), 111-123. http://dx.doi.org/10.1016/j.funbio.2015.10.010
Kebede, A.Z., Woldemariam, T., Reid, L.M., Harris, L.J. (2016). Quantitative trait loci mapping for Gibberella ear rot resistance and associated agronomic traits using genotyping-by-sequencing in maize, 129(1), 17-29. http://dx.doi.org/10.1007/s00122-015-2600-3
Kennedy, M.A., Moffat, T.C., Gable, K., Ganesan, S., Niewola-Staszkowska, K., Johnston, A., Nislow, C., Giaever, G., Harris, L.J., Loewith, R., Zaremberg, V., Harper, M.E., Dunn, T., Bennett, S.A.L., Baetz, K. (2016). A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction, 6 http://dx.doi.org/10.1038/srep19332

2015

Ghobakhlou, A.F., Johnston, A., Harris, L., Antoun, H., Laberge, S. (2015). Microarray transcriptional profiling of Arctic Mesorhizobium strain N33 at low temperature provides insights into cold adaption strategies, 16(1), http://dx.doi.org/10.1186/s12864-015-1611-4
Subramaniam, R., Narayanan, S., Walkowiak, S., Wang, L., Joshi, M., Rocheleau, H., Ouellet, T., Harris, L.J. (2015). Leucine metabolism regulates TRI6 expression and affects deoxynivalenol production and virulence in Fusarium graminearum, 98(4), 760-769. http://dx.doi.org/10.1111/mmi.13155

2014

Kennedy, M.A., Gable, K., Niewola-Staszkowska, K., Abreu, S., Johnston, A., Harris, L.J., Reggiori, F., Loewith, R., Dunn, T., Bennett, S.A.L., and Baetz, K. (2014). "A neurotoxic glycerophosphocholine impacts PtdIns-4,5-bisphosphate and TOR2 signaling by altering ceramide biosynthesis in yeast.", PloS Genetics, 10(1). doi : 10.1371/journal.pgen.1004010.g001
Lysøe, E., Harris, L.J., Walkowiak, S., Subramaniam, R., Divon, H.H., Riiser, E.S., Llorens, C., Gabaldón, T., Kistler, H.C., Jonkers, W., Kolseth, A.K., Nielsen, K.F., Thrane, U., Frandsen, R.J.N. (2014). The genome of the generalist plant pathogen Fusarium avenaceum is enriched with genes involved in redox, signaling and secondary metabolism, 9(11), http://dx.doi.org/10.1371/journal.pone.0112703
Miller, J.D., Schaafsma, A.W., Bhatnagar, D., Bondy, G., Carbone, I., Harris, L.J., Harrison, G., Munkvold, G.P., Oswald, I.P., Pestka, J.J., Sharpe, L., Sumarah, M.W., Tittlemier, S.A., Zhou, T. (2014). Mycotoxins that affect the North American agri-food sector: State of the art and directions for the future, 7(1), 63-82. http://dx.doi.org/10.3920/WMJ2013.1624

2013

Harris, L.J., Ouellet, T., and Subramaniam, R. (2013). "Applying proteomics to investigate the interactions between pathogenic Fusarium species and their hosts.", in Brown, D.W. and Proctor, R.H. (eds.) - Fusarium: Genomics, Molecular and Cellular Biology, Caister Academic Press, Chapter 5.

2012

Balcerzak, M., Harris, L.J., Subramaniam, R., Ouellet, T. (2012). The feruloyl esterase gene family of Fusarium graminearum is differentially regulated by aromatic compounds and hosts, 116(4), 478-488. http://dx.doi.org/10.1016/j.funbio.2012.01.007
Kant, P., Gulati, A., Harris, L.J., Gleddie, S.C., Singh, J., and Pauls, K.P. (2012). "Transgenic corn plants with modified ribosomal protein L3 show decreased ear rot disease after inoculation with Fusarium graminearum.", Australian Journal of Crop Science, 6(12), pp. 1598-1605.
Qi, P.F., Johnston, A., Balcerzak, M., Rocheleau, H., Harris, L.J., Long, X.Y., Wei, Y.M., Zheng, Y.L., Ouellet, T. (2012). Effect of salicylic acid on Fusarium graminearum, the major causal agent of fusarium head blight in wheat, 116(3), 413-426. http://dx.doi.org/10.1016/j.funbio.2012.01.001

2011

Mohammadi, M., Anoop, V., Gleddie, S., Harris, L.J. (2011). Proteomic profiling of two maize inbreds during early gibberella ear rot infection, 11(18), 3675-3684. http://dx.doi.org/10.1002/pmic.201100177
Nasmith, C.G., Walkowiak, S., Wang, L., Leung, W.W.Y., Gong, Y., Johnston, A., Harris, L.J., Guttman, D.S., Subramaniam, R. (2011). Tri6 is a global transcription regulator in the phytopathogen fusarium graminearum, 7(9), http://dx.doi.org/10.1371/journal.ppat.1002266
Xu, Y., Badea, C., Tran, F., Frick, M., Schneiderman, D., Robert, L., Harris, L., Thomas, D., Tinker, N., Gaudet, D., Laroche, A. (2011). Next-Gen sequencing of the transcriptome of triticale, 9(2), 181-184. http://dx.doi.org/10.1017/S1479262111000281

2010

Berthelet, S., Usher, J., Shulist, K., Hamza, A., Maltez, N., Johnston, A., Fong, Y., Harris, L.J., Baetz, K. (2010). Functional genomics analysis of the Saccharomyces cerevisiae iron responsive transcription factor Aft1 reveals iron-independent functions, 185(3), 1111-1128. http://dx.doi.org/10.1534/genetics.110.117531
McCormick, S.P., Alexander, N.J., Harris, L.J. (2010). CLM1 of fusarium graminearum encodes a longiborneol synthase required for culmorin production, 76(1), 136-141. http://dx.doi.org/10.1128/AEM.02017-09

2009

Subramaniam, R., Nasmith, C.G., Harris, L.J., and Ouellet, T. (2009). "Insight into Fusarium-cereal pathogenesis.", in Bouarab, K., Brisson, N. and Daayf, F. (eds.) - Molecular Plant-Microbe Interactions, CABI Publishing, Chapter 13, pp. 319-336.

Other science related publications

2019

Nguyen HDT, Grunwald NJ, Abad ZG, Martin FN, Crouch J, Hambleton S, Dettman J, Liu M, Harris LJ, Castlebury L, Salagado-Salazar C, Cowger C, Ellouz O, Mollov D, Fall ML, Ling K, Griffifths J, Mahaffee W, Chen W, Sultata T, Yu Q, Carta LK, Skantar AM, Tambong J, Rogers E, Li S, Dumonceaux TJ, Widmer TL. The 2019 AAFC-USDA meeting on genotyping and monitoring of high-risk plant pathogens.

2018

Abstract Book of the 9th Canadian Workshop on Fusarium Head Blight & 4th Canadian Wheat Symposium, p. 49-50, https://www.cwfhb-cws.com/hotel-1/
Harris, L.J., Johnston, A., Hermans, A., Sproule, A., Xue, A., Overy, D. Exploring the genetic diversity and mycotoxigenic potential of Canadian Fusarium poae isolates. 9th Can. Workshop on Fusarium Head Blight & 4th Can. Wheat Symp., https://www.cwfhb-cws.com/hotel-1/ Winnipeg, MB, Nov 19-22, 2018. P. 51. Poster.
Plant Biology 2019 Abstract Book.
Proceedings of the 14th European Fusarium Seminar, Tulln, Austria, Apr 8-11, 2018, P. 27, Invited talk. https://www.efs14.at/program.php

2017

DesRoches, C.-D., Johnston, A., Luo, K., Harris, L.J., Zhao, H.-Y., Ouellet, T. 2017. Effect of L-tryptophan, tryptamine and indole-3 acetaldehyde on gene expression in Fusarium graminearum. GEO accession# GSE100318. deposited in the Gene Expression Omnibus (GEO) of the public database NCBI.
Harris, L.J., Bahadoor, A., Brauer, E., Bosnich, W., Schneiderman, D., Aubin, Y., Melanson, J., Khan, I., Gleddie, S., Blackwell, B. Novel Fusarium graminearum cyclic peptides possess phytotoxic activity. 29th Fungal Genetics Conference, Pacific Grove, CA, Mar 14-19, 2017. Poster presentation.
Kebede, A.Z., Harris, L.J.*, Johnston, A., Schneiderman, D., Bosnich, W., Woldemariam, T., Reid, L.M. Searching for candidate genes contributing to Fusarium graminearum resistance in a recombinant inbred population. 70th Northeast Corn Improvement Conference, Ottawa, ON, Feb 21-22, 2017. Oral presentation.

2016

Bahadoor, A., Bosnich, W., Schneiderman, D., Blackwell, B., Aubin, Y., Melanson, J., Gleddie, S., Harris, L.J. Discovery of Novel Fusarium Secondary Metabolites. Session 10, Book of Abstracts of Lectures and Posters, World Mycotoxin Forum, Winnipeg, MB, June 6-9, 2016, p. 69. Invited talk
Blackwell, B., Bahadoor, A., Bosnich, W., Schneiderman, D., Aubin, Y., Harris, L.J. NMR structural studies of Fusarium secondary metabolites. 29th Annual MOOT NMR Conference, Charlottetown, PEI, Sept 30 – Oct 2, 2016. Poster presentation.
Blackwell, B., Bahadoor, A., Bosnich, W., Schneiderman, D., Herweyer, D., Gräfenhan, T., Harris, L.J. Secondary metabolite profile of Canadian NX-2 Fusarium graminearum chemotypes. Proceedings of the 8th Can. Workshop on Fusarium Head Blight, Ottawa, ON Nov. 20-22, 2016. P. 66, Poster presentation.
Gleddie, S., Hermans, A., Gunter, A., Bahadoor, A., Harris, L.J. Using yeasts to study mycotoxin toxicity and interactions. Book of Abstracts of Lectures and Posters, Session 10, World Mycotoxin Forum, Winnipeg, MB, June 6-9, 2016, p. 69.
Harris, L.J.*, Bosnich, W., Johnston, A., Kwan, R., Schneiderman, D., Blackwell, B., Bahadoor, A., Gleddie, S. Examining Fusarium graminearum and Fusarium avenaceum interactions in durum wheat. Proceedings of the 8th Can. Workshop on Fusarium Head Blight, Ottawa, ON Nov. 20-22, 2016. P. 18, Invited talk.
Harris, L.J., Bosnich, W., Johnston, A., Kwan, R., Schneiderman, D., Blackwell, B., Bahadoor, A., Gleddie, S. Fusarium interspecies interactions during infection of durum wheat. Invited talk, Session 10, Proceedings of the 9th Conference of the World Mycotoxin Forum, p. 70, Winnipeg, MB, June 6-9, 2016.
Kebede, A., Johnston, A., Schneiderman, D., Bosnich, W., Reid, L.M., Harris, L.J. Candidate gene identification for maize gibberella ear rot disease resistance using genomic and transcriptomic approaches. 5th International Conference on Quantitative Genetics, Madison, Wisconsin, June 12-17, 2016.
Kebede, A.Z., Johnston, A., Schneiderman, D., Bosnich, W., Reid, L.M., Harris, L.J. Combining QTL mapping with transcriptomics to identify candidate genes for Fusarium resistance in maize. Proceedings of the 8th Can. Workshop on Fusarium Head Blight, Ottawa, ON Nov. 20-22, 2016. P. 49, Poster presentation.

2015

Harris, L.J., Bosnich, W., Johnston, A., Kwan, R., Schneiderman, D., Blackwell, B.A., and Bahadoor, A. (2015). "A F. graminearum ABC transporter is induced during interactions with F. avenaceum and by enniatin B1.", 13th European Fusarium Seminar, Martina Franca, Italy, May 10-14, 2015, Poster, pp. 121. (Abstract)
Harris, L.J., Bosnich, W., Johnston, A., Kwan, R., Schneiderman, D., Blackwell, B.A., and Bahadoor, A. (2015). "Interaction studies between Fusarium graminearum and F. avenaceum during durum wheat infection.", 28th Fungal Genetics Conference, Pacific Grove, CA, USA, March 17-22, 2015. (Abstract)
Kebede, A.Z., Johnston, A., Schneiderman, D., Bosnich, W., and Harris, L.J. (2015). "Whole genome gene expression profiles of two inbred lines with distinct resistance to gibberella ear rot disease of maize.", 3rd Plant Genomics Congress USA-Global Engage, St. Louis, MO, USA, September 14-15, 2015. (Abstract)
Kebede, A.Z., Woldemariam, T., Reid, L.M., and Harris, L.J. (2015). "Molecular mapping of Gibberella ear rot resistance and kernel drydown rate in maize.", 13th European Fusarium Seminar, Martina Franca, Italy, May 10-14, 2015, pp. 168. (Abstract)
Kebede, A.Z., Woldemariam, T., Reid, L.M., and Harris, L.J. (2015). "Molecular mapping of gibberella ear rot resistance and kernel drydown rate in maize.", 57th Annual Maize Genetics Conference, Charles, IL, USA, March 12-15, 2015. (Abstract)

2013

Bala, K., Blackwell, B.A., Morales, A.Z., Johnston, A., Brown, C., Schneiderman, D., Gleddie, S.C., and Harris, L.J. (2013). "Interactions between different Fusarium species to uncover multi-toxin synergistic mechanisms.", The 12th European Fusarium Seminar, Bordeaux, France, May 12-16, 2013, pp. 100.
Gleddie, S.C., Harris, L.J., Hermans, A., Mitchell, L.G., Baetz, K., and Bosnich, W. (2013). "Fusarium fungal toxin screens against yeast genome deletion collections to define novel resistance mechanisms.", Plant & Animal Genome XIV Conference, Town & Country Convention Center, San Diego, CA, USA, January 14-18, 2006.
Harris, L.J., Johnston, A., Bosnich, W., LeBlanc, A., Blackwell, B.A., and Schneiderman, D. (2013). "Elucidation of the Fusarium graminearum butenolide biosynthetic gene cluster.", The 12th European Fusarium Seminar, Bordeaux, France, May 12-16, 2013, Invited talk, pp. 42.
Harris, L.J., Johnston, A., Bosnich, W., LeBlanc, A., Schneiderman, D., and Blackwell, B.A. (2013). "Elucidation of the Fusarium graminearum butenolide biosynthetic gene cluster.", Gordon Research Conference, Mycotoxins & Phycotoxins, Easton, MA, USA, June 16-21, 2013. (Poster)
Laroche, A., Xu, Y., Penniket, C., Robert, L.S., Robert, L.S., Harris, L.J., Tran, F., Schneiderman, D., Gulick, P.J., and Frick, M. (2013). "A comprehensive reference transcriptome for triticale (x Triticosecale Wittm.)", The 8th International Triticale Symposium, Ghent, Belgium, June 10-14, 2013, O10.
Xu, Y., Frick, M., Penniket, C., Robert, L.S., Harris, L.J., Tran, F., Schneiderman, D., Gulick, P.J., and Laroche, A. (2013). "Identification and regulation of cell wall transcripts in triticale (x Triticosecale Wittm.)", The 8th International Triticale Symposium, Ghent, Belgium, June 10-14, 2013, pp. 3. (Poster)
Zuniga, A., Bosnich, W., Bala, K., Harris, L.J., Gleddie, S.C., and Mester, Z. (2013). "LC-MS/MS-based structural analysis of novel enniatins produced by Canadian strains of Fusarium avenaceum in liquid culture.", 61st American Society of Mass Spectrometry Conference, Minneapolis, MN, USA, June 9-13, 2013. (Poster)

2012

Frick, M., Xu, Y., Penniket, C., Robert, L.S., Harris, L.J., Tran, F., Schneiderman, D., Gulick, P., and Laroche, A. (2012). "A triticale (x Triticosecale Wittm.) reference transcriptome.", 22nd International Triticeae Mapping Initiative (ITMI) and 4th National Wheat Genomics Committee Joint Workshop, Fargo, ND, USA, June 25-29, 2012, pp. 12.

2011

Allard, G.C., Subramaniam, R., Ouellet, T., Harris, L.J., and Singh, J. (2011). "Rapid screening of Arabidopsis mutants to identify transporter genes for resistance to Fusarium graminearum.", 7th Canadian Workshop on Fusarium Head Blight (CWFHB) / Colloque canadien sur la fusariose, Delta Winnipeg Hotel, Winnipeg, MB, Canada, November 27-30, 2011, pp. 100.
Frick, M., Xu, Y., Robert, L.S., Gulick, P., Harris, L.J., Badea, C., Penniket, C., and Laroche, A. (2011). "Transcriptional analyses of plant defense pathway related genes in cereals.", VI International Scientific Seminar on Plant Health and II International Phytoplasma Workshop, Havana, Cuba, September 22-26, 2008, pp. 13.
Gleddie, S.C., Hermans, A., Mitchell, L., Baetz, K., Bosnich, W., and Harris, L.J. (2011). "Yeast genome deletion screening identifies new cellular targets of the Fusarium graminearum fungal toxin deoxynivalenol.", 7th Canadian Workshop on Fusarium Head Blight (CWFHB) / Colloque canadien sur la fusariose, Delta Winnipeg Hotel, Winnipeg, MB, Canada, November 27-30, 2011, pp. 94.
Harris, L.J., Balcerzak, M., Schneiderman, D., Johnson, A., and Ouellet, T. (2011). "Transcriptome profiles of F. graminearum during infection of wheat, barley, and maize.", 26th Fungal Genetics Conference (26thFCG), Asilomar, CA, USA, March 15-20, 2011, Poster.
Harris, L.J., Bosnich, W., Johnston, A., Woldemariam, T., Reid, L.M., Schneiderman, D., Mohammadi, M., and Gleddie, S.C. (2011). "Mapping gibberella ear rot resistance in maize using a large B73 X CO441 F₆ recombinant inbred population.", 7th Canadian Workshop on Fusarium Head Blight (CWFHB) / Colloque canadien sur la fusariose, Delta Winnipeg Hotel, Winnipeg, MB, Canada, November 27-30, 2011, pp. 95.

2010

Balcerzak, M., Schneiderman, D., Johnson, A., Harris, L.J., and Ouellet, T. (2010). "Transcriptome Analysis Of Fusarium Graminearum During Infection of Three Monocot Hosts.", 11th European Fusarium Seminar: Fusarium - Mycotoxins, Taxonomy, Pathogenicity and Host Resistance, Plant Breeding and Acclimatization Institute (IHAR), Radzików, Poland, September 20-23, 2010, Poster #1. (Poster)
DesRoches, C., Balcerzak, M., Blackwell, B.A., Johnston, A., Harris, L.J., and Ouellet, T. (2010). "Investigating the Pathways and Genes Responsible for the Production of Indole-3-Acetic Acid by {I}Fusarium Graminearum{/I}.", 11th European Fusarium Seminar: Fusarium - Mycotoxins, Taxonomy, Pathogenicity and Host Resistance, Plant Breeding and Acclimatization Institute (IHAR), Radzików, Poland, September 20-23, 2010, Poster #51. (Poster)
Laroche, A., Xu, Y., Badea, C., Tran, F., Robert, L.S., Harris, L.J., Thomas, D.K., Tinker, N.A., Gaudet, D.A., and Frick, M. (2010). "Transcriptome studies to improve stripe rust resistance in cereals.", ESA-PPSA-WFPM, Lethbridge, AB, Canada, pp. 10.
Usher, J., Johnston, A., Harris, L.J., and Baetz, K. (2010). "The introduction of the exogenous gene XYLA improves xylose utilization in S. cerevisiae.", Cellulosic Biofuel Network (CBN) 2nd Annual General Meeting, Ottawa Marriott Hotel, Ottawa, ON, Canada, March 11-12, 2010, Poster #110, pp. 56. (Poster)
Yanofsky, C., Usher, J., Baetz, K., Montazeri, Z., Johnston, A., Harris, L.J., Mohammadi, M., Gleddie, S.C., and Bickel, D. (2010). "Analysis of -omics data: Application to the transcriptome of xylose-utilizing yeast.", Cellulosic Biofuel Network (CBN) 2nd Annual General Meeting, Ottawa Marriott Hotel, Ottawa, ON, Canada, March 11-12, 2010, Poster #106, pp. 55. (Poster)