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Epigenetics and the evolution of virulence.

Kasuga, T. and Gijzen, M. (2013). "Epigenetics and the evolution of virulence.", Trends in Microbiology, 21(11), pp. 575-582. doi : 10.1016/j.tim.2013.09.003  Access to full text


A feature of pathogenic and invasive organisms is their adaptability when confronted with host and environmental challenges. Recent studies have demonstrated that plant pathogens rely on epigenetic processes for this purpose. Epiallelic variation of effector genes that results in evasion of host immunity is one emerging phenomenon. Another is the epigenetically induced reprogramming and diversification of transcriptional patterns by de-repression of transposable elements. These observations indicate that epigenetic control of gene expression provides a versatile means of generating phenotypic diversity that is adaptable and heritable across generations.

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