Hegedus, Dwayne, Ph.D.

Plant Protection and Molecular Biology

Contact Information:

107 Science Place
Saskatoon, Saskatchewan S7N 0X2
Telephone: 306-385-9427
Fax: 306-385-9482
Email: dwayne.hegedus@agr.gc.ca

Areas of Expertise:

  • Disease and insect resistance
  • Plant, fungal and insect molecular biology and biochemistry
  • Recombinant protein expression

Current Projects:

  • Platforms for the expression of recombinant proteins in seeds. The focus is on developing systems to reduce endogenous seed storage protein accumulation and studying the biology of seed protein trafficking and comparmentalization.
  • Insect genomics and proteomics platforms leading to the identification of novel targets and strategies for insect resistance. The focus is on insect digestive biochemistry.
  • Sclerotinia sclerotiorum-Brassica napus interactions and identification of genes/markers for stem rot resistance in canola.


  • Adjunct Professor, Department of Food and Bio-Product Sciences, College of Agriculture, University of Saskatchewan, Saskatoon, SK, Canada

Research Publications:

The links below lead to abstracts with access to full text.




  • Gao, M.-J., Li, X.L., Lui, H., Gropp, G.M., Lydiate, D.J., Wei, S., and Hegedus, D.D. (2011). "ASIL1 is required for proper timing of seed filling in Arabidopsis.", Plant Signaling & Behavior, 6(12), pp. 1886-1888. doi : 10.4161/psb.6.12.18709
  • Li, X.L., Gruber, M.Y., Hegedus, D.D., Lydiate, D.J., and Gao, M.-J. (2011). "Effects of a Coumarin Derivative, 4-Methylumbelliferone, on Seed Germination and Seedling Establishment in Arabidopsis.", Journal of Chemical Ecology, 37(8), pp. 880-890. doi : 10.1007/s10886-011-9987-3
  • Terenius, O., Papanicolaou, A., Garbutt, J.S., Eleftherianos, I., Huvenne, H., Kanginakudru, S., Albrechtsen, M., An, C., Aymeric, J.-L., Barthel, A., Bebas, P., Bitra, K., Bravo, A., Chevalier, F., Collinge, D.P., Crava, C.M., de Maagd, R.A., Duvic, B., Erlandson, M.A., Faye, I., Felföldi, G., Fujiwara, H., Futahashi, R., Gandhe, A.S., Gatehouse, H.S., Gatehouse, L.N., Giebultowicz, J.M., Gómez, I., Grimmelikhuijzen, C.J.P., Groot, A.T., Hauser, F., Heckel, D.G., Hegedus, D.D., Hrycaj, S., Huang, L., Hull, J.J., Iatrou, K., Iga, M., Kanost, M.R., Kotwica, J., Li, C., Li, J., Liu, J., Lundmark, M., Matsumoto, S., Meyering-Vos, M., Millichap, P.J., Monteiro, A., Mrinal, N., Niimi, T., Nowara, D., Ohnishi, A., Oostra, V., Ozaki, K., Papakonstantinou, M., Popadic, A., Rajam, M.V., Saenko, S., Simpson, A.J., Soberón, M., Strand, M.R., Tomita, S., Toprak, U., Wang, P., Wee, C.W., Whyard, S., Zhang, W., Nagaraju, J., Gordon, R.H.J., Herrerop, S., Gordon, K., Smagghe, G., and Swevers, L. (2011). "RNA interference in Lepidoptera: An overview of successful and unsuccessful studies and implications for experimental design.", Journal of Insect Physiology, 57(2), pp. 231-245. doi : 10.1016/j.jinsphys.2010.11.006
  • Withana-Gamage, T.S., Hegedus, D.D., Qiu, X., and Wanasundara, P.K.J.P.D. (2011). "In Silico Homology Modeling To Predict Functional Properties of Cruciferin.", Journal of Agricultural and Food Chemistry, 59(24), pp. 12925-12938. doi : 10.1021/jf201979a



Other Science Related Publications:


  • Bahar, M.H., Soroka, J.J., Hegedus, D.D., and Dosdall, L.M. (2012). "Thermal tolerance and HSP70 gene expression in DBM and Diadegma insulare.", Entomological Society of Canada 62nd and Entomological Society of Alberta 60th joint Annual Meeting, Coast Edmonton Plaza Hotel, Edmonton, AB, Canada, November 4-7, 2012, #7. (Abstract)


  • Buchwaldt, L., Lydiate, D.J., Yu, F.Q., Hegedus, D.D., and Rimmer, S.R. (2011). "QTLs contributing to sclerotinia stem rot resistance in Brassica napus Zhongyou 821.", 13th International Rapeseed Congress, Prague, Czech Republic, June 5-9, 2011.
  • Fu, F., Harrington, M., Hegedus, D.D., Bekkaoui, D.R., Parkin, I.A.P., and Buchwaldt, L. (2011). "Co-location of defence genes from expression studies with QTLs conferring sclerotinia resitance in Brassica napus.", 8th Canadian Plant Genomics Workshop, Niagara Falls, ON, Canada, August 22-25, 2011. (Workshop)
  • Gyawali, S., Buchwaldt, L., Harrington, M., Parkin, I.A.P., Bekkaoui, D.R., Horner, K., Higgins, E.E., and Hegedus, D.D. (2011). "Association mapping of stem rot resistance in a world collection of Brassica napus.", American Phytopathological Society (APS) 2011 Joint Annual Meeting & International Association for the Plant Protection Sciences (IPPC), Honolulu, HI, USA, August 6-10, 2011.
  • Hannoufa, A., Wei, S., Gruber, M.Y., Khachatourians, G.G., Wang, Y., Hegedus, D.D., and Parkin, I.A.P. (2011). "MicroRNA156: A new player in regulating carotenoid accumulation in plants.", Canadian Society of Plant Physiologists Eastern Regional Meeting & Plant Development Workshop / Congrès de la Société Canadienne de Physiologie Végétale & Congrès de Développement Végétale (Congrès Régional de l’Est), Carleton University, Ottawa, ON, Canada, December 2-3, 2011, SB-1, pp. 17.
  • Kutcher, H.R., Dokken-Bouchard, F.L., Turkington, T.K., Fernando, W.G.D., Boyetchko, S.M., Buchwaldt, L., Hegedus, D.D., and Parkin, I.A.P. (2011). "Managing sclerotinia stem rot in canola.", Canola Research Summit meeting, Winnipeg, MB, Canada, April 12-13, 2011.
  • Noakes, A.L., Gillott, C., Hegedus, D.D., Theilmann, D.A., and Erlandson, M.A. (2011). "Mamestra configurata nucleopolyhedrovirus (MacoNPV): potential chitin-binding proteins and their role in oral infectivity.", 44th Annual Meeting of the Society for Invertebrate Pathology, Halifax, NS, Canada, August 7-11, 2011.
  • Sanjeewa, W.G.T., Hegedus, D.D., Yu, P., Qiu, X., McIntosh, T.C., May, T.W., and Wanasundara, P.K.J.P.D. (2011). "Influence of seed storage protein composition on structural features of major crucifer proteins: Protein secondary structure study of Arabiopsis thaliana.", 102nd Annual Meeting of the American Oil Chemists' Society (AOCS) & Expo, Duke Energy Center, Cincinnati, OH, USA, May 1-4, 2011.


  • Zhao, J., Buchwaldt, L., Rimmer, S.R., Sharpe, A.G., McGregor, L., Bekkaoui, D.R., and Hegedus, D.D. (2009). "Patterns of gene expression in Brassica napus cultivars infected with Sclerotinia sclerotiorum.", 14th International Sclerotinia Workshop, Wilmington, NC, USA, May 31-June 4, 2009. (Workshop)
  • Zhao, J., Buchwaldt, L., Rimmer, S.R., Sharpe, A.G., McGregor, L., Bekkaoui, D.R., and Hegedus, D.D. (2009). "Patterns of gene expression in Brassica napus cultivars infected with Sclerotinia sclerotiorum.", 7th Canadian Plant Genomics Workshop, Sheraton Cavalier Hotel, Saskatoon, SK, Canada, August 24-27, 2009. (Workshop)