Lessard, Martin, agr., Ph.D.

Research Scientist


Contact Information:

2000 College Street
Sherbrooke, Quebec J1M 0C8
Telephone: 819-7807220
Fax: 819-564-5507
Email: martin.lessard@agr.gc.ca

Areas of Expertise:

  • Influence of nutrition on the immune response and intestinal microbiota of pigs
  • Characterization of the immunoregulatory properties of functional foods and probiotics
  • Regulatory mechanisms involved in inflammation and intestinal immune response

Current Projects:

  • Study and evaluation of a new protein matrix for protecting probiotic bacteria against gastric conditions
  • Development of dietary strategies and technology to improve intestinal health and mitigate the use of antibiotics in monogastric animal productions
  • Development of novel feeding strategies aiming to improve gut development, defence functions, health and performance of piglets
  • Study of serocolostrum's impact on the expression of inflammatory response genes in porcine epithelial intestinal IPEC J2 cells
  • Efficacy of feed additives to mitigate the negative impacts of mycotoxin contaminated feed on performance and health of piglets
  • Integrated approach based on the use of bacteriocinogenic probiotics for controlling enteric pathogens in the pork chain

Affiliations:

  • Adjunct Professor, Université Laval, Animal Science
  • Adjunct professor, Département de pathologie et de microbiologie, Faculté de médecine vétérinaire, Université de Montréal
  • Adjunct professor, Department of Biology, Sherbrooke University
  • Associate Member, Institute of Nutraceuticals and Functional Foods (INAF), Université Laval
  • Associate Member, Swine Infectious Disease Research Centre (CRIP), Université de Montréal

Research Publications:

The links below lead to abstracts with access to full text.

2016

  • Topp, E., Irwin, R., McAllister, T.A., Lessard, M., Joensuu, J.J., Kolotilin, I., Conrad, U., Stöger, E., Mor, T., Warzecha, H., Hall, J.C., McLean, M.D, Cox, E., Devriendt, B., Potter, A., Depicker, A., Virdi, V., Holbrook, L., Doshi, K., Dussault, M., Friendship, R.M., Yarosh, O., Yoo, H.S., MacDonald, J.D., and Menassa, R. (2016). "The case for plant-made veterinary immunotherapeutics.", Biotechnology Advances. doi : 10.1016/j.biotechadv.2016.02.007

2015

2014

2013

2012

2011

2009

Other Science Related Publications:

2016

  • Lo Verso, L., Matte, J.J., Talbot, G., Bissonnette, N., Lapointe, J., Gagnon, N., Ouattara, B., Guay, F., and Lessard, M. (2016). "Effects of different sources and routes of administration of copper and vitamins A and D on gut volatile fatty acids and gene expression involved in regulation of innate and acquired immunity in piglets.", Journal of Animal Science, 94(Supp. 2). (Abstract)
  • Matte, J.J., Audet, I., Ouattara, B., Bissonnette, N., and Lessard, M. (2016). "Sources and routes of administration of copper and vitamins A and D on metabolic status of these micronutrients in suckling piglets.", Journal of Animal Science, 94(Supp. 2), pp. 116. (Abstract)
  • Talbot, G., Lessard, M., Yergeau, E., Gagnon, N., Lo Verso, L., Lapointe, J., Bissonnette, N., Bueno Dalto, D., Ouattara, B., Guay, F., and Matte, J.J. (2016). "Effects of different sources and routes of administration of copper and vitamins A and D on piglets gut microbiota.", Journal of Animal Science, 94(Supp. 2). (Abstract)
  • Talbot, G., Lessard, M., Yergeau, E., Gagnon, N., Lo Verso, L., Lapointe, J., Bissonnette, N., Bueno Dalto, D., Ouattara, B., Guay, F., and Matte, J.J. (2016). "Microbiota of the small intestine of piglets affected by perinatal administration of copper and vitamins A and D.", 18th International Conference on Microbiota Buenos Engineering, Buenos Aires, Argentina, 27-28 October, 2016.

2015

  • Bissonnette, N., Jiang, X-R., Matte, J.J., Talbot, G., Guay, F., Gong, J., Wang, Q., Bontempo, V., and Lessard, M. (2015). "Effect of a post-weanling diet supplemented with gut health-enhancing feed additives on ileum transcriptome activity and serum cytokines in piglets challenged with lipopolysaccharides (LPS)", ADSA-ASAS JAM (Joint Annual Meeting) 2015, Orlando, Florida, USA, July 12-16, 2015, 2-15, Poster Session.
  • Fomenky, B., Beaudoin, F., Chiquette, J., Talbot, G., Bissonnette, N., Chouinard, P.Y., Lessard, M., and Ibeagha-Awemu, E.M. (2015). "Amélioration du développement immunitaire chez les veaux laitiers par les probiotiques.", Symposium sur les bovins laitiers 2015, Drummondville, QC, Canada, Octobre 29, 2015.
  • Ibeagha-Awemu, E.M., Beaudoin, F., Chiquette, J., Talbot, G., Bissonnette, N., and Lessard, M. (2015). "Probiotics administration enhances calves’ lymphoproliferation responses to vaccination during the early weeks of growth.", 2015 Conference of the Canadian Society of Animal Science and the Canadian Meat Council, Ottawa, Canada, May 6-8, 2015.
  • Lessard, M. (2015). "La santé intestinale : Interactions entre l’alimentation, le microbiote et le système immunitaire.", Intégrer des ingrédients novateurs en alimentation porcine et avicole, Centre Québécois de valorisation des biotechnologies et Centre de développement du porc du Québec.

2014

  • Atia, A., Lessard, M., Beyssac, E., Garrait, G., Gomaa, A., Fliss, I., and Subirade, M. (2014). "Les probiotiques et l’alimentation porcine.", 6ième Colloque international francophone de microbiologie animale, École nationale vétérinaire de Toulouse, Toulouse, France, May 15-16, 2014.
  • Audet, I., Girard, C.L., Lessard, M., Lo Verso, L., and Matte, J.J. (2014). "Homocysteinemia, growth performance, and immune responses in suckling and weanling piglets.", Journal of Animal Science, 92(E-Suppl.2), pp. 219. (Abstract)
  • Bissonnette, N., Dudemaine, P.-L., Lessard, M., Labrecque, O., Roy, J.-P., and Fecteau, G. (2014). "Increased blood-circulating interferon gamma, interleukin 17 and osteopontin levels in bovine paratuberculosis.", 12th International Colloquium on Paratuberculosis, Parma, Italy, Abstract ID 3. (Abstract)
  • Le Thanh, B.V., Lessard, M., Chorfi, Y., and Guay, F. (2014). "Antioxidant activity of intestinal mucosa in piglets fed deoxynivalenol naturally contaminated diet.", ADSA-ASAS 2014 Joint Annual Meeting, Kansas City, MO, USA, July 20-24, 2014, Also published on J. Anim. Sci. 92 (E-Suppl. 2): 686.
  • Lessard, M., Bergeron, N., Deschêne, K., Matte, J.J., Guay, F., Bissonnette, N., Talbot, B.G., Gong, J., Wang, Q., Quessy, S., and Letellier, A. (2014). "Intestinal gene expression involved in innate and acquired immune responses of pigs is affected by Salmonella infection and diets supplemented with gut health-enhancing feed additives.", 23rd International Pig Veterinary Society Congress, Cancun, México, June 8-11, 2014, Abstract A1387. (Poster)
  • Lessard, M., Bergeron, N., Deschêne, K., Matte, J.J., Guay, F., Bissonnette, N., Talbot, B.G., Quessy, S., and Letellier, A. (2014). "Influence of Salmonella infection and diets supplemented with gut health-enhancing feed additives on expression of intestinal genes involved in immune response of pigs.", 7ième Symposium du CRIPA, Hyacinthe, Québec, Canada, 3-4 juin 2014. (Poster)
  • Lessard, M., Deschêne, K., Savard, C., Gagnon, A.-È., Lapointe, J., Pinilla, V.A., Guay, F., and Chorfi, Y. (2014). "Effect of deoxynivalenol (DON) ingestion on expression of genes involved in intestinal barrier and immune functions.", 7ième Symposium du CRIPA, Hyacinthe, Québec, Canada, 3-4 juin 2014, Présentation orale.
  • Lessard, M., Deschêne, K., Savard, C., Lapointe, J., Guay, F., and Chorfi, Y. (2014). "Effect of deoxynivalenol (DON) ingestion on expression of genes involved in intestinal integrity and immune response.", 2014 ADSA-ASAS Midwest Meeting, Iowa Events Center, Des Moines, Iowa, USA, March 17-19, 2014, # 163; Oral Présentation. (Abstract)
  • Morisette, B., Lessard, M., Yergeau, E., Lapointe, J., Guay, F., Bissonnette, N., Matte, J.J., Letellier, A., Quessy, S., Bergeron, N., Beaulieu, C., and Talbot, G. (2014). "Influence of Feed Additives as an Alternative to Antibiotics on Gut Microbiota of Weaned Piglets Infected with Salmonella Typhimurium.", 114th General Meeting of the American Society for Microbiology, Boston, Massachusetts, USA, May 17-20, 2014.
  • Morissette, B., Lessard, M., Yergeau, E., Lapointe, J., Guay, F., Bissonnette, N., Matte, J.J., Letellier, A., Quessy, S., Bergeron, N., and Talbot, B.G. (2014). "Influence of Feed Additives as an Alternative to Antibiotics on Gut Microbiota of Weaned Piglets Infected with Salmonella Typhimurium.", 7ième Symposium du CRIPA, Hyacinthe, Québec, Canada, 3-4 juin 2014. (Poster)

2013

  • Abdelbasset, A., Lo Verso, L., Fliss, I., Lessard, M., Talbot, G., and Subirade, M. (2013). "Protection of probiotic bacteria in a symbiotic matrix.", 6th Symposium of Swine and Poultry Infectious Diseases Research Center. Congrès de l’ACFAS Colloque 227 – Le microbiote animal : une question d’équilibre., Université Laval, Québec, QC, Canada, May 8-9, 2013. (Poster)
  • Atia, A., Fliss, I., Lessard, M., and Subirade, M. (2013). "Une matrice synbiotique pour la protection des probiotiques.", Symposium PROBIO 2013 "Probiotiques au-delà de la santé intestinale", Montréal, Québec, Canada, October 30-31, 2013.
  • Audet, I., Girard, C.L., Lessard, M., and Matte, J.J. (2013). "Métabolisme de l’homocystéine et performacnes de croissance chez le porcelet pendant l’allaitement et après le sevrage.", Journées d’Information scientifique en productions animales, Québec, Canada, pp. 28-29.
  • Bergeron, N., Lessard, M., Quessy, S., and Letellier, A. (2013). "Evaluation of feeding strategies to reduce Salmonella infection in piglets.", 12ème réunion annuelle du Réseau Canadien des Travailleurs des Laboratoires de Santé Animale (RCTLSA)/ Canadian Animal Health Laboratorians Network (CAHLN), St-Hyacinthe, Québec, Canada, May 27-29, 2013.
  • Bergeron, N., Lessard, M., Quessy, S., and Letellier, A. (2013). "Evaluation of the impact of functional food on the course of Salmonella infection in piglets.", SafePork, 9th International Symposium on the Epidemiology and Control of Foodborne Pathogens in Pork, Portland, Maine, USA, September 9-12, 2013.
  • Bergeron, N., Lessard, M., Quessy, S., and Letellier, A. (2013). "Feeding strategies to reduce Salmonella infection in piglets.", 6th Symposium of Swine and Poultry Infectious Diseases Research Center. Congrès de l’ACFAS Colloque 227 – Le microbiote animal : une question d’équilibre., Université Laval, Québec, QC, Canada, May 8-9, 2013.
  • Blais, M., Fortier, M.-È., Pouliot, Y., Gauthier, S.F., Boutin, B., and Lessard, M. (2013). "Decaseinated Colostrum Mediates Beneficial Effects On Cell Proliferation, Wound Healing And Inflammatory Response In Porcine Intestinal Epithelial Cells IPEC J2.", 7th Annual meeting of the International Society of Nutrigenetics and Nutrigenomics, October 5-8, 2013, Also published on Canada, J. Nutrigenet. Nutrigenomics 6:207.
  • Deschêne, K., Beaudoin, F., Lauzon, K., Cantin, D., and Lessard, M. (2013). "Expression of Intestinal Immune Genes in Nursing Piglets Is Modulated by Piglet Weight at Birth and their Growth in the First Week of Live.", 7th Annual meeting of the International Society of Nutrigenetics and Nutrigenomics, October 5-8, 2013, Also published on J. Nutrigenet. Nutrigenomics 6:218.
  • Dudemaine, P.-L., Fecteau, G., Lessard, M., Côté, G., Labrecque, O., Buczinski, S., Doré, E., Roy, J.-P., and Bissonnette, N. (2013). "Altered immune response in bovine paratuberculosis.", CSAS-CMSA Joint Annual Meeting, Banff Park Lodge Resort Hotel and Conference Centre, Banff, AB, Canada, June 18-20, 2013, # P05 page 26. (Abstract)
  • Lessard, M. (2013). "Mycotoxins and the Immune System.", Swine Innovation Porc, 1(15).
  • Lo Verso, L., Lessard, M., Talbot, G., Subirade, M., and Fliss, I. (2013). "Isolation and antibacterial activity of potential probiotic bacteria from pig gastrointestinal tract.", 6th Symposium of Swine and Poultry Infectious Diseases Research Center. Congrès de l’ACFAS Colloque 227 – Le microbiote animal : une question d’équilibre., Université Laval, Québec, QC, Canada, May 8-9, 2013, pp. 45. (Poster)
  • Morissette, B., Lessard, M., Guay, F., Matte, J.J., Gong, J., Wang, Q., Beaulieu, C., and Talbot, G. (2013). "Prebiotics, probiotic, nutraceuticals and functional food as feed additives that modulate the gut microbiota of weanling piglets challenged with E. coli lipopolysaccharides.", 63rd Annual Conference of the Canadian Society of Microbiologists, Carleton University, Ottawa, ON, Canada, June 17-20, 2013, Abstract AE56. (Abstract)
  • Talbot, G. and Lessard, M. (2013). "Influence of growth rate, probiotics, nutraceuticals and functional food on intestinal microbiota of suckling and weanling piglets.", 6th Symposium of Swine and Poultry Infectious Diseases Research Center. Congrès de l’ACFAS Colloque 227 – Le microbiote animal : une question d’équilibre., Université Laval, Québec, QC, Canada, May 8-9, 2013.

2012

  • Lessard, M. (2012). "Development of novel feeding strategies aiming to improve gut development, defence functions, health and performance of piglets.", Swine Cluster CA members seminar. (Presentation)
  • Lessard, M., Deschêne, K., Savard, C., and Chorfi, Y. (2012). "Effects of DON on porcine intestinal immunity.", Symposium sur les mycotoxines, AQINAC, ANAC et partenaires, Brossard, QC, Canada, December 11, 2012. (Presentation)
  • Morissette, B., Lessard, M., and Talbot, G. (2012). "Is there a link between piglet’s weight gain and its intestinal bacteria?", 2ème symposium du Centre de Recherche et de Développement sur le Bovin Laitier et le Porc / 2nd Annual DSRDC/ CRDBLP Symposium on Animal Production, Sherbrooke, QC, Canada, November 28, 2012.
  • Talbot, G., Morissette, B., and Lessard, M. (2012). "The impact of piglet weight gain on the intestinal microbiota during lactation.", Canadian Society of Microbiologists (CSM) 62nd Annual Conference / Conférence annuelle de la Société Canadienne des Microbiologistes (SCM), Vancouver, BC, Canada, June 20-23, 2012, Abstract II057. (Poster)

2011

  • Blais, M., Chambers, J.R., Beaudoin, F., Gauthier, S.F., Pouliot, Y., and Lessard, M. (2011). "Regulation of inflammatory genes by milk fractions in human and swine intestinal epithelial cells.", 4e symposium du Centre de Recherche en Infectiologie Porcine (CRIP), Université de Montréal, Saint-Hyacinthe, QC, Canada, Page 18. (Presentation)
  • Brousseau, J.P., Beaudoin, F., Lauzon, K., Talbot, G., Roy, D., and Lessard, M. (2011). "Effets de Pediococcus acidilactici et Saccharomyces cerevisiae boulardii sur le microbiote de l’iléon et du côlon chez le porcelet sevré.", 4e Symposium Annuel du Centre de Recherche en Infectiologie Porcine (CRIP), Université de Montréal, Saint-Hyacinthe, QC, Canada, May 30-31, 2011. (Abstract)
  • Chambers, J.R., Blais, M., Beaudoin, F., Gauthier, S.F., Pouliot, Y., and Lessard, M. (2011). "Effet du sérocolostrum sur l’expression de gènes de réponse inflammatoire dans les cellules épithéliales intestinales porcines IPEC J2 et les cellules de carcinome de côlon humain Caco-2/15.", XVII colloque annuel d'immuno-inflammation, Eastman, QC, Canada, June 17, 2011. (Presentation)
  • Michaud, N., Gauthier, S.F., Robitaille, G., Pouliot, Y., Tremblay, É., Beaulieu, J.-F., and Lessard, M. (2011). "Modulation de la réaction inflammatoire intestinale par des sous-produits du lait.", Colloque bisannuel du STELA la recherche laitière 2011, Hôtel Palace Royal, Québec City, QC, Canada, May 30-31, 2011.

2010

  • Bovey, K., Devillers, N., Lessard, M., Farmer, C., Dewey, C., Widowski, T.M., and Torrey, S. (2010). "The effect of birth weight and age on the behavioural and physiological responses of piglets to tail docking and ear notching.", 44th Congress of the International Society for Applied Ethology, University of Agricultural Sciences, Uppsala, Sweden, August 4-7, 2010, pp. 34.

2009

  • Alain, K., Karrow, N.A., Thibault, C., Lessard, M., and Bissonnette, N. (2009). "Development of a multiplex-PCR detection assay for simultaneous identification of the major pathogens causing mastitis in dairy milk.", Journal of Animal Science, 87(E-Suppl. 2), pp. 199-200 (#T6). (Abstract)
  • Alain, K., Karrow, N.A., Thibault, C., Lessard, M., and Bissonnette, N. (2009). "Innate immune responses in dairy cows and study of promising candidate: osteopontin.", Journal of Animal Science, 87(E-Suppl. 2), pp. 198-199 (#T3). (Abstract)
  • Beaudoin, F., Farmer, C., St-Pierre, G., Lachance, M.-P., and Lessard, M. (2009). "Influence of prolonged photoperiod on immune status of piglets.", 3rd European Veterinary Immunology Workshop (EVIW) Satellite meeting of the 2nd European Congress of Immunology (ECI 2009), Berlin, Germany, September 10-13, 2009, pp. 57.
  • Farmer, C., Giguère, A., Lessard, M., and Petit, H.V. (2009). "Feeding flax to late-pregnant and lactating sows: Effects on fatty acid profiles, hormones and performances of sows and their litters.", Journal of Animal Science, 87(Suppl. 2), pp. 64. (Abstract)
  • Lessard, M., Petit, H.V., Giguère, A., and Farmer, C. (2009). "Feeding flax to late-pregnant and lactating sows: Effects on sow immunity and antibody transfer to their piglets.", Journal of Animal Science, 87(Suppl. 2), pp. 62-63. (Abstract)
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