Lacasse, Pierre, Ph.D.

Research Scientist


Contact Information:

2000 College Street
Sherbrooke, Quebec J1M 0C8
Telephone: 819-780-7236
Fax: 819-564-5507
Email: pierre.lacasse@agr.gc.ca

Areas of Expertise:

  • dairy cattle
  • herd management
  • lactation biology
  • mammary gland physiology
  • mammary gland metabolism
  • endocrinology
  • cell culture
  • cellular and molecular biology
  • immunology and vaccination

Current Projects:

  • Control of lactation persistency in dairy cows
  • Innovative periparturient dairy cow management to improve cow’s immune functions and productivity
  • Innovative dairy cow management: redefining drying-off
  • Management of drying-off and susceptibility to new intramammary infection
  • Characterization of virulence factors of Staphylococcus aureus
  • Development of a vaccine to prevent mastitis caused by Staphylococcus aureus
  • Development of new treatments to cure mastitis caused by Staphylococcus aureus

Affiliations:

  • Director of the "Animal" component of the Canadian Bovine Mastitis Research Network
  • Associate Professor, Department of Biology, University of Sherbrooke
  • Associate Professor, Department of Animal Science, Laval University
  • Associate Professor, Department of Animal Science, McGill University

Research Publications:

The links below lead to abstracts with access to full text.

2014

2013

2012

2011

2010

2009

Other Science Related Publications:

2012

  • Côté-Gravel, J., Ster, C., Allard, M., Gagnon, S., Boulanger, S., Mulhbacher, J., Lafontaine, D.A., Scholl, D., Diarra, M.S., Lacasse, P., and Malouin, F. (2012). "Mise en évidence des gènes utilisés par Staphylococcus aureus pendant l’infection intra-mammaire et utilisation de ceux-ci comme cibles thérapeutiques: développement d’une nouvelle classe d’antibiotique et d’un vaccin contre S. aureus pour le contrôle de la mammite bovine.", Forum Technologique NOVALAIT / IDF Dairy Science and Technology Week 2012, Hôtel et Suites Le Dauphin, Drummondville, QC, Canada, May 29, 2012.
  • Lacasse, P. and Zhao, X. (2012). "Régie novatrice des troupeaux laitiers québécois : repenser le tarissement.", Forum Technologique NOVALAIT / IDF Dairy Science and Technology Week 2012, Hôtel et Suites Le Dauphin, Drummondville, QC, Canada, May 29, 2012, P2012-02. (Abstract)
  • Malouin, F., Ster, C., Talbot, B.G., Potter, A., and Lacasse, P. (2012). "Protective effect of vaccination using Staphylococcus aureus antigens that are only expressed during bovine intramammary infections: challenge in dairy cows.", Canadian Bovine Mastitis Research Network (CBMRN) Annual Scientific Meeting 2012, Montréal, QC, Canada, November 22-23, 2012, #P9. (Poster)
  • Malouin, F., Ster, C., Talbot, B.G., Scholl, D., Roy, J.-P., Dufour, S., Haine, D., Keefe, G., Macdonald, K., and Lacasse, P. (2012). "Validation of Staphylococcus aureus virulence markers as prognostic tools for intramammary persistence.", Canadian Bovine Mastitis Research Network (CBMRN) Annual Scientific Meeting 2012, Montréal, QC, Canada, November 22-23, 2012, pp. 8.
  • Ollier, S., Zhao, X., Talbot, B.G., and Lacasse, P. (2012). "Effects of feed restriction and prolactin-release inhibition at drying-off on milk production, metabolism and mammary gland involution.", Canadian Bovine Mastitis Research Network (CBMRN) Annual Scientific Meeting 2012, Montréal, QC, Canada, November 22-23, 2012. (Poster)
  • Ollier, S., Zhao, X., Talbot, B.G., and Lacasse, P. (2012). "Management of Drying-off and susceptibility to new IMI.", Canadian Bovine Mastitis Research Network (CBMRN) Annual Scientific Meeting 2012, Montréal, QC, Canada, November 22-23, 2012, P14. (Poster)
  • Ollier, S., Zhao, X., and Lacasse, P. (2012). "Effects of feed restriction and prolactin-release inhibition at drying-off on milk production, metabolism and mammary gland involution.", ADSA-AMPA-ASAS-CSAS-WSASAS 2012 Joint Annual Meeting, Hyatt Regency, Phoenix, AZ, USA, July 15-19, 2012, Published in: J. Dairy Sci. Vol. 95, E-Suppl. 1: 301 (T134). (Abstract)
  • Ponchon, B., Lacasse, P., Silanikove, N., and Zhao, X. (2012). "Effects of intra-mammary infusions of casein hydrolysate, EGTA, and lactose at drying-off on mammary gland involution.", ADSA-AMPA-ASAS-CSAS-WSASAS 2012 Joint Annual Meeting, Hyatt Regency, Phoenix, AZ, USA, July 15-19, 2012, Published in: J. Dairy Sci. Vol. 95, E-Suppl. 1: 553 (W150). (Poster)
  • Ster, C., Côté-Gravel, J., Allard, M., Gagnon, S., Potter, A., Talbot, B.G., Lacasse, P., and Malouin, F. (2012). "A focus on genes expressed by Staphylococcus aureus during bovine intramammary infection for vaccine development.", World Dairy Summit 2012, Cape Town, South Africa, November 4-8, 2012.
  • Veh, K.A., Ster, C., Jacob, C.L., Talbot, B.G., Scholl, D., Roy, J.-P., Dufour, S., Keefe, G., Haine, D., Macdonald, K., Lacasse, P., and Malouin, F. (2012). "Validation of Staphylococcus aureus Virulence Markers as Prognostic Tools for Intramammary Persistence.", Canadian Bovine Mastitis Research Network (CBMRN) Annual Scientific Meeting 2012, Montréal, QC, Canada, November 22-23, 2012. (Poster)

2011

  • Bernier-Dodier, P., Lacasse, P., Tremblay, G.F., and Tremblay, G. (2011). "Characterization of a novel bovine mammary epithelial cell line.", Journal of Dairy Science (JDS), 94(E-Suppl. 1), pp. 76 (#M196). (Abstract)
  • Borucki Castro, S.I., Berthiaume, R.R., Robichaud, A., and Lacasse, P. (2011). "Effects of predipping practices on milk iodine concentrations.", Journal of Dairy Science (JDS), 94(E-Suppl. 1), pp. 301 (#T106). (Abstract)
  • Lacasse, P. (2011). "Improvement of cow wellbeing and resistance to mastitis.", Dairy Research Cluster: Communications and Consultation Workshop - Shaping a dairy research agenda for 2013 - 2018, Queen Elizabeth Hotel, Montréal, QC, Canada, November 16-17, 2011.
  • Lacasse, P., Lollivier, V., Bruckmaier, R.M., Ollier, S., and Boutinaud, M. (2011). "New developments on the galactopoietic role of prolactin in dairy ruminants.", 7th International Congress on Farm Animal Endocrinology (ICFAE 2011), Bern, Switzerland, August 24-26, 2011, pp. 20-21.
  • Ollier, S. and Lacasse, P. (2011). "Tarir sans réduire la capacité à combattre la mammite.", Le Producteur de Lait Québécois, 32(1), pp. 56-57.
  • Ollier, S., Maisonnasse, P., Bernier-Dodier, P., and Lacasse, P. (2011). "Factors affecting the milking-induced prolactin release in dairy cows.", 7th International Congress on Farm Animal Endocrinology (ICFAE 2011), Bern, Switzerland, August 24-26, 2011, pp. 21-22. (Abstract)
  • Ollier, S., Zhao, X., Talbot, B.G., and Lacasse, P. (2011). "Effect of drying-off management on milk production, metabolism and mammary gland involution.", Canadian Bovine Mastitis Research Network (CBMRN) Annual Scientific Meeting 2011, Montréal, QC, Canada, November 8-9, 2011. (Poster)
  • Ollier, S., Zhao, X., Talbot, B.G., and Lacasse, P. (2011). "Effect of drying-off management on milk production, metabolism and mammary gland involution.", Dairy Research Cluster: Communications and Consultation Workshop - Shaping a dairy research agenda for 2013 - 2018, Queen Elizabeth Hotel, Montréal, QC, Canada, November 16-17, 2011. (Poster)
  • Ollier, S., Zhao, X., and Lacasse, P. (2011). "Effect of prolactin-release inhibition on milk production and mammary gland involution at drying-off.", ADSA-PSA-AMPA-CSAS-ASAS 2011 Joint Annual Meeting, New Orleans, LA, USA, July 11-14, 2011, Published in: Journal of Dairy Science (JDS), 94(E-Suppl. 1), pp. 564 (#W147). (Abstract)
  • Ster, C., Boulanger, S., Allard, M., Talbot, B.G., Lacasse, P., and Malouin, F. (2011). "Vaccine Potential of Proteins Encoded by Genes Expressed by Staphylococcus aureus During Bovine Mastitis.", Canadian Bovine Mastitis Research Network (CBMRN) Annual Scientific Meeting 2010, Toronto, ON, Canada, November 10-12, 2010. (Poster)
  • Ster, C., Lacasse, P., Mulhbacher, J., Allard, M., Brouillette, É., Lafontaine, D.A., and Malouin, F. (2011). "A Novel Class of Riboswitch-Targeting Antibiotics for the Treatment of Staphylococcus aureus Bovine intra-Mammary infections (IMI).", 51st Interscience conference on Antimicrobial agents and Chermotherapy (ICAAC), Chicago, IL, USA, September 17-20, 2011, pp. F1-1353.
  • Ster, C., Lacasse, P., Talbot, B.G., and Malouin, F. (2011). "Finding the weapons used by Staphylococcus aureus during bovine intra-mammary infection and use of this knowledge for the development of a new class of antibiotics and a vaccine.", Canadian Bovine Mastitis Research Network (CBMRN) Annual Scientific Meeting 2011, Montréal, QC, Canada, November 8-9, 2011. (Poster)
  • Ster, C., Scholl, D., Roy, J.-P., Keefe, G., Lacasse, P., Talbot, B.G., and Malouin, F. (2011). "Validation of Staphylococcus aureus virulence markers as prognostic tools for intramammary persistence.", Canadian Bovine Mastitis Research Network (CBMRN) Annual Scientific Meeting 2011, Montréal, QC, Canada, November 8-9, 2011. (Poster)

2010

  • Allard, M., Ster, C., Jacob, C.L., Diarra, M.S., Lacasse, P., and Malouin, F. (2010). "Identification of Genes Expressed by Staphylococcus aureus During Bovine Mastitis for Vaccine and Drug Development.", 5th IDF Mastitis conference, Christchurch Convention Centre, Christchurch, New Zealand, March 21-24, 2010, pp. 342-347.
  • Allard, M., Ster, C., Talbot, B.G., Diarra, M.S., Scholl, D., Lacasse, P., and Malouin, F. (2010). "Evaluation of Genes Expressed by S. aureus During Bovine Mastitis as Potential Vaccine Candidates or Drug Targets.", Canadian Bovine Mastitis Research Network (CBMRN) Annual Scientific Meeting 2010, Toronto, ON, Canada, November 10-12, 2010. (Poster)
  • Borucki Castro, S.I., Berthiaume, R.R., Fouquet, A., Robichaud, A., Beraldin, F., and Lacasse, P. (2010). "Effects of iodine intake and teat dipping practices on milk iodine concentrations.", Journal of Dairy Science (JDS), 93(E-Suppl. 1), pp. 45 (#M96). (Abstract)
  • Borucki Castro, S.I., Lacasse, P., Fouquet, A., Robichaud, A., Beraldin, F., and Berthiaume, R.R. (2010). "Iodine concentrations in feeds in farms with contrasting levels of iodine in milk.", Journal of Dairy Science (JDS), 93(E-sSuppl. 1), pp. 45 (#M97). (Abstract)
  • Boutinaud, M., Arizala, J.A., Bruckmaier, R.M., Lacasse, P., and Lollivier, V. (2010). "Milking-induced prolactin release has proliferative and survival roles on mammary epithelial cells in dairy cows.", 61st Annual Meeting of the European Association for Animal Production (EAAP), Crete, Greece, August 23-27, 2010.
  • Diarra, M.S., Kobylarz, M., Allard, M., Rempel, H., Brouillette, É., Lacasse, P., and Malouin, F. (2010). "In Vitro Expression of some Heme Related Genes in Staphylococcus aureus mutants.", 110th General Meeting of American Society for Microbiology (ASM2010), Town & Country Convention Center, San Diego, CA, USA, May 23-27, 2010. (Poster)
  • Lacasse, P., Bernier-Dodier, P., Ollier, S., Lollivier, V., and Boutinaud, M. (2010). "Mécanismes physiologiques de l’involution de la mamelle chez la vache.", Journées National des GTV, Lille, France, May 26-29, 2010, pp. 1015-1019. (Abstract)
  • Loiselle, M.C. and Lacasse, P. (2010). "Effect of serum composition on the functionality of bovine peripheral blood mononuclear cells.", 91st Annual Meeting of the Conference of Research Workers in Animal Disease (CRWAD), Chicago, IL, USA, December 5-7, 2010.
  • Palin, M.-F., Petit, H.V., Beaudry, D., Côrtes, C., Gagnon, N., Lacasse, P., and Benchaar, C. (2010). "Effect of flax oil and flax hulls on mRNA abundance of antioxidant enzymes and lipogenic-related genes in the mammary gland of dairy cows.", Journal of Animal Science, 88(E-Suppl. 2), pp. 717 (#W405). (Abstract)
  • Scholl, D.T., Barkema, H.W., Lacasse, P., and Tomita, G.M. (2010). "Successes and Pitfalls of the Canadian Industry-Partnership Approach to Mastitis Research.", 5th IDF Mastitis conference, Christchurch Convention Centre, Christchurch, New Zealand, March 21-24, 2010, pp. 152-156.
  • Ster, C., Allard, M., Boulanger, S., Talbot, B.G., Lacasse, P., and Malouin, F. (2010). "Identification of Staphylococcus aureus genes highly expressed during bovine mastitis: A unique opportunity for vaccine development.", 91st Annual Meeting of the Conference of Research Workers in Animal Disease (CRWAD), Chicago, IL, USA, December 5-7, 2010.
  • Ster, C., Diarra, M.S., Lacasse, P., Talbot, B.G., and Malouin, F. (2010). "Cyclic Diguanylate: A New Tool for the Control of Staplylococcus aureus- induced Bovine Mastitis?", 5th IDF Mastitis conference, Christchurch Convention Centre, Christchurch, New Zealand, March 21-24, 2010, pp. 291-294.

2009

  • Allard, M., Ster, C., Talbot, B.G., Diarra, M.S., Scholl, D., Lacasse, P., and Malouin, F. (2009). "Evaluation of genes expressed by S. aureus during bovine mastitis as potential vaccine candidates or drug targets.", 2009 Annual Scientific Meeting of the Canadian Bovine Mastitis Research Network (CBMRN), Montréal, QC, Canada, October 26-28, 2009.
  • Bernier-Dodier, P.Talbot, B.G., Lacasse, P. (2009). "Effect of a shortened dry period on the mammary gland physiology.", Journal of Dairy Science (JDS), 92(E-Suppl. 1), pp. 333. (Abstract)
  • Blouin, J., Ster, C., Lacasse, P., Jacques, M., Malouin, F., and Diarra, M.S. (2009). "Cloning and Expression of Some Iron-Regulated Genes of Bovine Mastitis Staphylococcus aureus.", 27th Western Canadian Dairy Seminar (WCDS): Forging Ahead Through Challenging, Capri Centre, Red Deer, AB, Canada, March 10-13, 2009.
  • Borucki Castro, S.I., Berthiaume, R.R., Fouquet, A., Beraldin, F., Robichaud, A., and Lacasse, P. (2009). "Iodine levels in milk from Canadian farms.", 13th Annual Federal Food Safety and Nutrition Research Meeting (FFSNRM), Ottawa, ON, Canada, November 4-5, 2009.
  • Borucki Castro, S.I., Berthiaume, R.R., Turcot, S., Robichaud, A., and Lacasse, P. (2009). "Iodine levels in Canadian bulk-tank milk.", Journal of Dairy Science (JDS), 92(E-Suppl. 1), pp. 272. (Abstract)
  • Boutinaud, M., Lollivier, V., Bruckmaier, R.M., and Lacasse, P. (2009). "Transcripts in Milk Purified Mammary Epithelial Cells Can Reveal the Effect of Once Daily Milking.", 6th International Symposium on Milk Genomics & Human Health, Mercure Paris Porte de Versailles Expo, Paris, France, September 28-30, 2009.
  • Chedly, H.B., Lacasse, P., Marnet, P.-G., Wiart-Letort, S., Finot, L., and Boutinaud, M. (2009). "Cell junction disruption after 36h milk accumulation was associated with changes in mammary secretory tissue activity and dynamics in lactating dairy goats.", Journal of Physiology and Pharmacology, 60(Suppl. 3), pp. 105-111.
  • Lafrance, M., Rivest, M., Lacasse, P., Talbot, B.G., and Malouin, F. (2009). "Vaccination against Staphylococcus aureus.", 2009 Annual Scientific Meeting of the Canadian Bovine Mastitis Research Network (CBMRN), Montréal, QC, Canada, October 26-28, 2009.
  • Lollivier, V., Bruckmaier, R.M., Lacasse, P., and Boutinaud, M. (2009). "Effect of the milking-induced prolactin release on galactopoiesis in dairy cows.", Journal of Dairy Science (JDS), 92(E-Suppl. 1), pp. 507. (Abstract)
  • Petit, H.V., Côrtes, C., Gagnon, N., Palin, M.-F., Tao, S., Benchaar, C., and Lacasse, P. (2009). "Flax hulls and oil supplementation on the activity of antioxidant enzymes in dairy cows.", XIth International Symposium on Ruminant Physiology, Clermont-Ferrand, France, September 6-9, 2009, pp. 630-631.
  • Villeneuve, L., Cinq-Mars, D., and Lacasse, P. (2009). "Effects of restricted feeding of prepubertal ewe lamb on growth performance, mammary gland development and first lactation.", Journal of Animal Science, 92(E-Suppl. 1), pp. 46. (Abstract)
  • Villeneuve, L., Cinq-Mars, D., and Lacasse, P. (2009). "Finalité du projet agnelles de remplacement : deux lactations plus tard… .", Ovin Québec, 9(4), pp. 31-32.