Theilmann, David, Ph.D.

A/Research Manager - Research Scientist Molecular Insect Virology


Contact Information:

4200 Highway 97
Box 5000
Summerland, British Columbia V0H 1Z0
Telephone: 250-494-6395
Fax: 250-494-0755
Email: david.theilmann@agr.gc.ca

Areas of Expertise:

  • insect diseases - viral
  • genomics
  • molecular virology
  • entomology
  • biological control
  • gene expression

Current Projects:

  • In vivo functional interactions of a baculovirus pathogen with the midgut of its host the Lepidopteran pest insects
  • Global analysis of tissue specific gene expression during infection of the canola pest Mamestra configurata by its baculovirus pathogen MacoNPV
  • Molecular analyses of baculovirus proteins required for attachment and infection of the midgut of its host the Lepidopteran Canola Pest Mamestra configurata.
  • Molecular analyses of the baculovirus pathogenic for the greenhouse pest Trichoplusia ni
  • Development of midgut genomics and proteomics platform leading to the identification of novel insect targets for enhanced resistance.

Affiliations:

  • Adjunct Professor Faculty of Land and Food Systems University of British Columbia
  • Adjunct Professor Zoology Department University of British Columbia
  • Baculovirus Genome consultant for the National Institutes of Health GenBank Nucleic acid and protein data base
  • Member of the Biocontrol Network
  • Member and Past Chair of the baculovirus study group of the International Committee for the Taxonomy of Viruses

Research Publications:

The links below lead to abstracts with access to full text.

2016

  • Javed MA, Biswas S, Willis LG, Harris S, Pritchard C, van Oers MM, Donly BC, Erlandson MA, Hegedus DD, Theilmann DA. 2017. Autographa californica multiple nucleopolyhedrovirus AC83 is a per os infectivity factor (PIF) protein required for occlusion-derived virus (ODV) and budded virus nucleocapsid assembly as well as assembly of the PIF complex in ODV envelopes. J Virol 91:e02115-16.
  • Javed, M.A., Harris, S., Willis, L.G., Theilmann, D.A., Donly, B.C., Hegedus, D.D., Erlandson, M.A. (2016) Microscopic investigation of AcMNPV infection in the Trichoplusia ni midgut. J. Invert. Pathology. 141:24-33.

2015

2014

2013

2012

2011

2010

2009

Other Science Related Publications:

2016

  • Donly, C., Kaplanoglu, E., Theilmann, D., Hegedus, D., Baldwin, D., Siemenska, E., Erlandson, M. (2016) Measuring the Mamestra configurata Nucleopolyhedrosis Virus Transcriptome: Personalized Insect Genomics. Insect Biotech Conference, St. Catharines, Ontario. 8-10 June 2016, oral presentation.

2015

  • Erlandson, M.A., Harris, S., Sieminska, E.A., Baldwin, D., Hegedus, D.D., and Theilmann, D.A. (2015). "Inhibition of Cotesia vanessae development in Trichoplusia ni larvae infected with alphabaculoviruses from Mamestra configurata.", 48th Annual Meeting of the Society for Invertebrate Pathology and International Congress on Invertebrate Pathology and Microbial Control, Vancouver, B.C., Canada, August 9-13, 2015, Oral Presentation.
  • Harrison, R.L., Theilmann, D.A., and Erlandson, M.A. (2015). "Genome sequence analysis of a two alphabaculoviruses and a betabaculovirus from armyworms of the genus Mythimna.", 48th Annual Meeting of the Society for Invertebrate Pathology and International Congress on Invertebrate Pathology and Microbial Control, Vancouver, B.C., Canada, August 9-13, 2015. (Poster)
  • Javed, M.A., Harris, S., Theilmann, D.A., Erlandson, M.A., and Hegedus, D.D. (2015). "AcMNPV infection process in Trichoplusia ni midgut.", 48th Annual Meeting of the Society for Invertebrate Pathology and International Congress on Invertebrate Pathology and Microbial Control, Vancouver, B.C., Canada, August 9-13, 2015. (Poster)
  • Theilmann, D.A., Willis, L.G., Weis, M.M., Donly, B.C., Hegedus, D.D., and Erlandson, M.A. (2015). "Analysis of occlusion derived virus infection in tissue culture using gene knock out viruses of the per os infectivity factors and GP64.", 48th Annual Meeting of the Society for Invertebrate Pathology and International Congress on Invertebrate Pathology and Microbial Control, Vancouver, B.C., Canada, August 9-13, 2015, Oral Presentation.

2014

  • Baldwin, D., Theilmann, D.A., Vlak, J.M., and Erlandson, M.A. (2014). "Genomic variation of Mamestra configurata nucleopolyhedroviruses from noctuid host species across Holarctic regions.", 2014 Joint Annual Meeting of Entomological Society of Saskatchewan and Entomological Society of Canada, Saskatoon SK, Canada, September 28-October 1, 2014. (Poster)
  • Biswas, S., Blissard, G.W., and Theilmann, D.A. (2014). "Analysis of Autographa californica multiple nucleopolyhedrovirus (AcMNPV) AC141 (EXON0) interaction with the lepidoptern Trichoplusia ni (T. ni) kinesin-1.", XVIth International Congress of Virology - International Union of Microbiological Societies (IUMS 2014), July 27 - August 1, 2014, Montréal, Québec, Canada, July 27-August 1, 2014, oral presentation, pp. 392.
  • Biswas, S., Blissard, G.W., and Theilmann, D.A. (2014). "Investigations into the role of Autographa californica multiple nucleopolyhedrovirus (AcMNPV) AC141 (EXON0) and Trichoplusia ni kinesin-1 in budded virus nucleocapsid egress.", 47th Annual Meeting of the Society for Invertebrate Pathology and International Congress on Invertebrate Pathology and Microbial Control, Johannes Gutenberg University, Mainz, Germany, August 3-7, 2014, pp. 44.
  • Erlandson, M.A., Donly, B.C., Theilmann, D.A., Hegedus, D.D., Coutu, C., and Baldwin, D. (2014). "Mamestra configurata nucleopolyhedrovirus-A transcriptome from infected host midgut.", 47th Annual Meeting of the Society for Invertebrate Pathology and International Congress on Invertebrate Pathology and Microbial Control, Johannes Gutenberg University, Mainz, Germany, August 3-7, 2014, oral presentation, pp. 80.
  • Erlandson, M.A., Donly, B.C., Theilmann, D.A., Hegedus, D.D., Coutu, C., and Baldwin, D. (2014). "Mamestra configurata nucleopolyhedrovirus-A transcriptome from infected host midgut.", 47th Annual Meeting of the Society for Invertebrate Pathology and International Congress on Invertebrate Pathology and Microbial Control, Mainz, Germany, August 3-7, 2014, Oral Presentation.
  • Erlandson, M.A., Theilmann, D.A., Hegedus, D.L., Donly, T., Gariepy, T.D., and Olfert, O.O. (2014). Bertha armyworm (Mamestra configurata): Genomics, population dynamics and biodiversity of pest and pathogens. Annual Project Report to AAFC-Genomics. (Report)
  • Harris, S., Sieminska, E., Theilmann, D.A., Hegedus, D.D., and Erlandson, M.A. (2014). "Interaction between baculovirus infection and Cotesia parasitism in Trichoplusia ni larvae.", 2014 Joint Annual Meeting of Entomological Society of Saskatchewan and Entomological Society of Canada, Saskatoon SK, Canada, September 28-October 1, 2014. (Poster)

2013

  • Donly, B.C., Theilmann, D.A., Hegedus, D.D., Baldwin, D., and Erlandson, M.A. (2013). "Viral transcription in caterpillar gut infected with the Mamestra configurata nucleopolyhedrosis virus.", Insect Biotech Conference 2013, St. Catharines, Ontario, Canada.

2012

  • Maghodia, A.B., Fang, M.G., Theilmann, D.A., and Erlandson, M.A. (2012). "A group II alphabaculovirus core gene, MacoNPV-A pif-5 (odv-e56), cannot repair the essential per os infectivity function of the AcMNPV-pif5 knockout virus in Trichoplusia ni larvae.", 45th Annual Meeting of the Society for Invertebrate Pathology: 2012 International Congress on Invertebrate Pathology and Microbial Control, Centro de Convenciones UCA, Puerto Madero, Buenos Aires, Argentina, August 5-9, 2012, pp. 127.
  • Peng, K., van Lent, J.W.M., Boeren, S., Theilmann, D.A., Erlandson, M.A., Vlak, J.M., and van Oers, M.M. (2012). "Characterization of novel components of the baculovirus per os infectivity factor (PIF) complex.", 45th Annual Meeting of the Society for Invertebrate Pathology: 2012 International Congress on Invertebrate Pathology and Microbial Control, Centro de Convenciones UCA, Puerto Madero, Buenos Aires, Argentina, August 5-9, 2012, pp. 127.

2011

  • Erlandson, M.A., Maghodia, A.B., Cossentine, J.E., Lowery, D.T., and Theilmann, D.A. (2011). "Genome structure of a nucleopolyhedrovirus infecting Abagrotis reedi, a cutworm pest of vineyards.", 44th Annual Meeting of the Society for Invertebrate Pathology, Halifax, NS, Canada, August 7-11, 2011. (Poster)
  • Nie, Y., Fang, M.G., Erlandson, M.A., and Theilmann, D.A. (2011). "Deletion analysis of the AcMNPV gene ac67 (lef-3) encoding the single stranded DNA binding protein and the core gene ac68 shows that LEF-3 is not essential for virus replication.", 30th Annual Meeting of American Society for Virology, University of Minnesota, Minneapolis, MN, USA, July 16-20, 2011.
  • Noakes, A.L., Gillott, C., Hegedus, D.D., Theilmann, D.A., and Erlandson, M.A. (2011). "Mamestra configurata nucleopolyhedrovirus (MacoNPV): potential chitin-binding proteins and their role in oral infectivity.", 44th Annual Meeting of the Society for Invertebrate Pathology, Halifax, NS, Canada, August 7-11, 2011.

2010

  • Erlandson, M.A., Links, M.G., Maghodia, A.B., Donly, B.C., Hegedus, D.D., and Theilmann, D.A. (2010). "Mamestra configurata nucleopolyhedrovirus strain variation at the genome sequence level.", Society for Invertebrate Pathology Conference 2010, Trabzon, Turkey.
  • Toprak, U., Baldwin, D., Hegedus, D.D., Gillott, C., Harris, S., Theilmann, D.A., and Erlandson, M.A. (2010). "Mamestra configurata nucleopolyhedrovirus ENHANCIN substrate specificity and insect intestinal mucin structural types.", Society for Invertebrate Pathology Conference 2010, Trabzon, Turkey.

2009

  • Erlandson, M.A., Links, M.G., Ethier, S., Toprak, U., Hegedus, D.D., and Theilmann, D.A. (2009). "Baculoviruses associated with Mamestra configurata (Bertha Armyworm): Role of viral enhancing factor (VEF) in the infection process.", 8th Workshop on the Molecular Biology and Genetics of the Lepidoptera, Crete, Greece.
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