Sanfaçon, Hélène, Ph.D.

Research Scientist


Contact Information:

4200 Hiaghway 97
PO Box 5000
Summerland, British Columbia V0H 1Z0
Telephone: 250-494-6393
Fax: 250-494-0755
Email: helene.sanfacon@agr.gc.ca

Areas of Expertise:

  • molecular biology of plant viruses
  • methodology development for plant virus resistance
  • characterization of plant virus replication complexes
  • characterization of host factors involved in virus replication
  • study of viral proteases and design of inhibitors
  • characterization of tomato ringspot virus
  • development of genetic resistance to plum pox virus
  • characterization of viruses infecting fruit trees and small fruits

Current Projects:

  • Characterization of replication and translation complexes associated with plant RNA viruses (Sanfacon)
  • Development of genetic resistance to Plum pox virus in Canada

Affiliations:

  • Adjunct Professor, Dept. Botany, University of British Columbia
  • Chair Comoviridae study group, International Committee for the Taxonomy of Viruses
  • Associate Editor, Canadian Journal of Botany

Research Publications:

The links below lead to abstracts with access to full text.

2016

2015

2014

2013

2011

2010

2009

Other Science Related Publications:

2015

  • Wei, T., Chisholm, J., and Sanfaçon, H. (2015). "Cleavage of tomato ringspot virus NTP-binding protein by the membrane-associated signal peptidase.", 34th Annual Meeting of American Society for Virology, London, Ontario, Canada, July 11-15, 2015. (Abstract)

2014

  • Ghoshal, B. and Sanfaçon, H. (2014). "Temperature-dependent symptom recovery in Nicotiana benthamiana plants infected with tomato ringspot virus is associated with reduced translation of viral RNA2 and requires ARGONAUTE 1.", International Union of Microbiological Societies Congress (IUMS 2014), Montréal, QC, Canada, July 27-August 1, 2014. (Poster)
  • Sanfaçon, H. (2014). "Updates to the Plant Virus Taxonomy.", International Union of Microbiological Societies Congresses, Montreal, QC, Canada, July 27-August 1, 2014. (Poster)
  • Wei, T. and Sanfaçon, H. (2014). "Evidence for in vitro and in vivo cleavage of the C-terminal region of the tomato ringspot virus NTP-binding protein by the membrane-associated signal peptidase.", International Union of Microbiological Societies Congress (IUMS 2014), Montréal, QC, Canada, July 27-August 1, 2014. (Poster)

2013

  • Ghoshal, B. and Sanfaçon, H. (2013). "Symptom recovery in Nicotiana benthamiana plants infected with tomato ringspot virus is associated with Argonaute 1-dependent translational repression of the viral genome.", Keystone Symposium: RNA Silencing, Whistler Conference Centre, Whistler, BC, Canada, March 19-24, 2013. (Poster)
  • Stobbs, L.W., Hunter, D.M., Samara, R., Lowery, T., Lowery, D.T., and Sanfaçon, H. (2013). "Progress in Epidemiological Research on Plum Pox Virus.", The Tender Fruit Grape Vine (for Commercial Fruit Growers), 17(5), pp. 5-6. (Newsletter)
  • Tian, L.-N., Wang, X., Svircev, A.M., Wang, A.M., Sanfaçon, H., Brown, D.C.W., Kohalmi, S.E., and Lu, M. (2013). "Development of Plum pox virus resistance in plum grown in Canada via plant biotechnology.", 2nd International Symposium on Plum Pox Virus, Olomouc, Czech Republic, September 3-6, 2013.
  • Wang, A.M., Elhiti, M., Wang, H., Li, Y., Tian, L.-N., Svircev, A.M., Sanfaçon, H., and Brown, D.C.W. (2013). "Development of genetic resistance to Plum pox virus in Canada.", 2nd International Symposium on Plum Pox Virus, Olomouc, Czech Republic, September 3-6, 2013.

2012

  • Sanfaçon, H., Walker, M.C., Jovel, J., Karran, R., Ghoshal, B., Chisholm, J., and Wei, T. (2012). "In depth study of the interaction of peach viruses with plant defense responses for improved management of PPV.", Joint Canadian Phytopathological Society (CPS) 83rd Annual Meeting and International PPV Meeting, Marriott Gateway On The Falls, Niagara Falls, ON, Canada, June 24-27, 2012. (Presentation)
  • Tian, L.-N., Wang, X., Kohalmi, S.E., Svircev, A.M., Wang, A.M., Sanfaçon, H., Brown, D.C.W., and Schneider, K.E. (2012). "Control of the expression of the host factor eIF(iso)4E gene for Plum Pox Virus resistance.", Joint Canadian Phytopathological Society (CPS) 83rd Annual Meeting and International PPV Meeting, Marriott Gateway On The Falls, Niagara Falls, ON, Canada, June 24-27, 2012. (Presentation)
  • Wei, T., Chisholm, J., and Sanfaçon, H. (2012). "Stability of the tomato ringspot virus RNA-dependent RNA polymerase in plants: exploring possible interactions with components of the proteaseome and with caspase-like proteases.", XV International Congress of Virology, Sapporo, Japan, September 11-16, 2011. (Abstract)

2011

  • Ghoshal, B. and Sanfaçon, H. (2011). "Accumulation of viral products during the symptomatic and recovery phase in Nicotiana benthamiana plants infected with tomato ringspot virus isolates differing in their virulence.", XV International Congress of Virology, Sapporo, Japan, September 11-16, 2011. (Presentation)
  • Sanfaçon, H. and Fuchs, M. (2011). "Tomato ringspot virus.", in Hadidi, A., Barba, M., Candresse, T., and Jelkmann, W. (eds.) - Virus and Virus-Like Diseases of Pome and Stone Fruits, American Phytopathological Society (APS), Chapter 9, Part II. Pome Fruit Viruses and Related Diseases.
  • Sanfaçon, H., Gorbalenya, A.E., Knowles, N.J., and Chen, Y. (2011). "Order Picornavirales.", in King, A.M.Q., Adams, M.J., Carstens, E.B. and Lefkowitz, E.J. (eds.) - Virus Taxonomy: Ninth Report of the International Committee on Taxonomy of Viruses, Elsevier, pp. 835-839.
  • Sanfaçon, H., Iwanami, T., Karasev, A.V., van der Vlugt, R., Wellink, J., Wetzel, T., and Yoshikawa, N. (2011). "Family Secoviridae.", in King, A.M.Q., Adams, M.J., Carstens, E.B. and Lefkowitz, E.J. (eds.) - Virus Taxonomy: Ninth Report of the International Committee on Taxonomy of Viruses, Elsevier, pp. 881-899.
  • Wei, T., Chisholm, J., and Sanfaçon, H. (2011). "Sequence analysis of RNA1-encoded replication proteins of tomato ringspot nepovirus isolates.", XV International Congress of Virology, Sapporo, Japan, September 11-16, 2011. (Poster)

2010

  • Brown, D.C.W., Wang, A.M., Tian, L.-N., Svircev, A.M., Sanfaçon, H., and Miki, B.L.A. (2010 Internal). Developmnt of genetic resistance to PPV in Prunus Sp. Research Report to the Plum Pox Virus Working Group, St. Catherines, Ontario, January 26-28, 2010. (Report)
  • Sanfaçon, H. (2010). "Emerging technologies for the control of plant virus diseases.", in Wang, A. (ed.) - Principles and Practice of Advanced Technology in Plant Virology, Research Signpost, Kerala, India, Chapter 17, pp. 295-310.
  • Tian, L.-N., Svircev, A.M., Sanfaçon, H., and Brown, D.C.W. (2010). "Plum pox virus resistance stability and expression of specific siRNAs in plum.", US/Canada Plum Pox Virus Update and International Research Symposium, Kearneysville, WV, USA, January 4-6, 2010.

2009

  • Brown, D.C.W., Wang, A.M., Tian, L.-N., Svircev, A.M., Sanfaçon, H., and Miki, B.L.A. (2009 Internal). Developing genetic resistance to Plum Pox Virus. Research Report to the Plum Pox Virus Working Group, St Catherines, Ontario, January 27, 2009. (Report)
  • Le Gall, O., Sanfaçon, H., Ikegami, M., Iwanami, T., Jones, T., Karasev, A.V., Lehto, K., Wellink, J., Wetzel, T., and Yoshikawa, N. (2009). "Cheravirus and Sadwavirus: Two unassigned genera of plant positive-sense single-stranded RNA viruses formerly considered atypical members of the genus Nepovirus (family Comoviridae) [Archives of Virology 152(9), pp.1767-1774] (Erratum).", Archives of Virology, 154(6), pp. 1019.
Date modified: