Li, Changxi, Ph.D.

Research Scientist, Beef Genomics

Contact Information:

4-10 Agr/For Centre
University of Alberta
Edmonton, Alberta T6G 2P5
Telephone: 780-492-5248
Fax: 780-492-4265
Email: changxi.li@agr.gc.ca

Areas of Expertise:

  • Identification and characterization of genes for economically important traits including growth, fat deposition, carcass merit and feed efficiency in beef cattle through quantitative trait loci (QTL) mapping, candidate gene research and gene expression analyses;
  • Validation of gene or DNA maker-trait associations and implementation of marker or gene assisted selection in beef cattle genetic evaluation and breeding programs.

Current Projects:

  • Whole-genome positional candidate gene association analyses for fat deposition and carcass merit in beef cattle using a high-density SNP marker set.
  • Validation of SNP marker associations with fat deposition and carcass merit using a SNP allele specific gene expression analysis.
  • Identification of genes and gene by environment interactions affecting net feed efficiency in cattle.
  • Multiple and candidate gene approaches to evaluation and improvement of economically relevant traits in cattle.

Affiliations:

  • Adjunct Professor, University of Alberta, Department of Agricultural, Food and Nutritional Science

Research publications

2018

2017

2016

  • Akanno, E. C., L. Chen, M. K. Abo-Ismail, J. J. Crowley, Z. Wang, C. Li, J. A. Basarab, M. MacNeil, and G. S. Plastow. 2017. Genomic prediction of breed composition and heterosis effects in Angus, Charolais and Hereford crosses using 50K genotypes. Can. J. Anim. Sci. 97: 431–438, dx.doi.org/10.1139/cjas-2016-0124.
  • Lu, D., Akanno, E.C., Crowley, J.J., Schenkel, F.S., Li, H., De Pauw, M., Moore, S.S., Wang, Z., Li, C., Stothard, P., Plastow, G., Miller, S.P., and Basarab, J.A. (2016). "Accuracy of genomic predictions for feed efficiency traits of beef cattle using 50K and imputed HD genotypes.", Journal of Animal Science, 94(4), pp. 1342-1353. doi : 10.2527/jas.2015-0126
  • Yining Wang, Guohui Lin, Changxi Li, Paul Stothard. Genotype Imputation Methods and Their Effects on Genomic Predictions in Cattle. Springer Science Reviews (2016) 4:79–98. DOI 10.1007/s40362-017-0041-x.

2015

2014

2013

2012

2011

2009

Other science related publications

2016

  • Foroutan, A., Dugan, M.E.R, Stothard, P., Grant, J., Paradis, F., Guan, L.L., McAllister, T.A., Basu, U., Li, C., and Fitzsimmons, C.J. (2016). "Gene expression differences associated with fatty-acid deposition in beef cattle fed diets with supplemental flaxseed.", XXIV Plant and Animal Genomics Conference, San Diego, CA, USA, January 2016. (Abstract)

2015

  • Li, C., Ekine-Dzivenu, C., Chen, L., Vinsky, M.D., Basarab, J.A., Aalhus, J.L., Dugan, M.E.R, and Fitzsimmons, C.J. (2015). "Heritability estimates and accuracy of predicting direct genomic breeding values for fatty acid composition of beef cattle.", CASA. (Abstract)
  • Luo, H., Harasymow, S., Paynter, B., Li, C., MacLeod, A., and O'Donovan, J.T. (2015). "Genetic and environmental effects on barley and malt proteins from two Australian and two Canadian varieties.", 17th Australian Barley Technical Symposium, Manley, NSW, Australia, September 13-18, 2015. (Abstract)

2014

  • Akanno, E.C., Plastow, G., Li, C., Miller, S.P., and Basarab, J.A. (2014). "Accuracy of Molecular Breeding Values for Production and Efficiency Traits of Canadian Crossbred Beef Cattle Using a Cross-Validation Approach.", 10th World Congress on Genetics Applied to Livestock Production (WCGALP), Vancouver, Canada, August 17-22, 2014, Paper 513 & poster presentation.
  • Chen, L., Karisa, B.K., Li, C., and Plastow, G. (2014). "Development and utilization of genomic tools to exploit genetic diversity and heterosis in Canadian beef cattle populations.", Beef and Ranch Report, pp. 11-13.
  • Chen, L., Karisa, B.K., Li, C., and Plastow, G. (2014). "Development and utilization of genomic tools to exploit genetic diversity and heterosis in Canadian beef cattle populations.", University of Alberta Kinsella Day, Kinsella, AB, Canada, August 13, 2014. (Poster)
  • Chen, L., Plastow, G., and Li, C. (2014). "Estimating variance components for growth, feed efficiency and carcass merit traits in Angus steers using additive and dominance genomic relationship matrices.", 10th World Congress on Genetics Applied to Livestock Production (WCGALP), Vancouver, Canada, August 17-22, 2014, Paper 461.
  • Chen, L., Vinsky, M.D., Ekine, C., Basarab, J.A., Aalhus, J.L., Dugan, M.E.R, Curtis, J., Fitzsimmons, C.J., Stothard, P., and Li, C. (2014). "Genomic prediction of direct genomic breeding values for fatty acid concentrations in subcutaneous adipose and longissimus lumborum muscle of beef cattle.", Livestock Gentec 5th Annual conference, Edmonton, AB, Canada, August 12-14, 2014. (Poster)
  • Crowley, J.J., Stothard, P., Basarab, J.A., Miller, S.P., Li, C., Wang, Z., Plastow, G., De Pauw, E., Moore, S.S., and Lu, D. (2014). "Collation of Data and Genetic Parameter Estimation in Different Experimental Canadian Beef Cattle Populations Measured for Feed Efficiency.", 10th World Congress on Genetics Applied to Livestock Production (WCGALP), Vancouver, Canada, August 17-22, 2014, Paper 117.
  • Fitzsimmons, C.J., Muhire, G., Paradis, F., McKeown, L.E., Straathof, C., Block, H.C., Colazo, M.G., Li, C., Yaremcio, B., Basarab, J.A., and Bruce, H.L. (2014). "Pregnant beef heifers categorized by residual feed intake measured in adolescence exhibit differential intake andfeeding behaviors when fed a restricted diet. 2014.", ADSA-ASAS 2014 Joint Annual Meeting, Kansas City, MO, USA, July 20-24, 2014. (Poster)
  • Jin, L., Li, C., He, M.L., Wang, Y., Alexander, T.W., and McAllister, T.A. (2014). "Effects of echium and flaxseed oil on ruminal fatty acid metabolism in vitro.", ADSA-ASAS 2014 Joint Annual Meeting, Kansas City, MO, USA, July 20-24, 2014.
  • Khansefid, M., Pryce, J.E., Bolormaa, S., Miller, S.P., Wang, Z., Li, C., and Goddard, M.E. (2014). "Increasing the Accuracy of Genomic Predictions for RFI in Dairy Cattle through Using Genomic Information from Beef Breeds.", 10th World Congress on Genetics Applied to Livestock Production (WCGALP), Vancouver, Canada, August 17-22, 2014, Paper 113.
  • Li, C., Aalhus, J.L., Dugan, M.E.R, Fitzsimmons, C.J., Basarab, J.A., Curtis, J., Stothard, P., Okine, E.K., Wang, Z., Bruce, H.L., and Buchanan, F.C. (2014). Identifying DNA markers for enhancing beneficial fatty acids in beef, Final project report, 33 pages to Alberta Livestock and Meat Agency (ALMA). (Report)
  • Li, C., Chen, L., and Vinsky, M.D. (2014). "Genomic Prediction for Feed Efficiency and Carcass Traits in Angus and Charolais Beef Cattle.", Beef and Ranch Report, pp. 20-21.
  • Li, C., Chen, L., and Vinsky, M.D. (2014). "Genomic Prediction for Feed Efficiency and Carcass Traits in Angus and Charolais Beef Cattle.", University of Alberta Kinsella Day, Kinsella, AB, Canada, August 13, 2014. (Poster)
  • Li, C., Dugan, M.E.R, Aalhus, J.L., Fitzsimmons, C.J., Basarab, J.A., Buchanan, F.C., Chen, L., Ekine-Dzivenu, C., Stothard, P., Curtis, J., Bruce, H.L., Wang, Z., and Okine, E.K. (2014). "Genetic Influence of Host Animal on Fatty Acid Profile in Beef.", University of Alberta Kinsella Day, Kinsella, AB, Canada, August 13, 2014. (Poster)
  • Li, C., Dugan, M.E.R, Aalhus, J.L., Fitzsimmons, C.J., Basarab, J.A., Buchanan, F.C., Chen, L., Ekine-Dzivenu, C., Stothard, P., Curtis, J.M., Bruce, H.L., Wang, Z., and Okine, E.K. (2014). "Genetic Influence of Host Animal on Fatty Acid Profile in Beef.", Beef and Ranch Report, pp. 34-35.
  • Li, C., Ekine-Dzivenu, C., Chen, L., Vinsky, M.D., Aldai, N., Dugan, M.E.R, and McAllister, T.A. (2014). "Heritability Estimates of Conjugated Linoleic Acid Isomers in Brisket Adipose Tissue of Canadian Crossbred Beef Steers.", 10th World Congress on Genetics Applied to Livestock Production (WCGALP), Vancouver, Canada, August 17-22, 2014, Paper 588 & Poster.
  • Lu, D., Crowley, J.J., Li, C., Coros, C., DePauw, M., Plastow, G., Moore, S.S., Miller, S.P., and Stothard, P. (2014). "Inbreeding in Canadian Beef Cattle Breeds.", 10th World Congress on Genetics Applied to Livestock Production (WCGALP), Vancouver, Canada, August 17-22, 2014. (Poster)
  • Lu, D., Crowley, J.J., Li, C., Coros, M., DePauw, M., Plastow, G., Moore, S.S., Miller, S.S., Miller, S.S., and Stothard, P. (2014). "Genomic Inbreeding Coefficients in a Sample of Canadian Beef Cattle Breeds.", 10th World Congress on Genetics Applied to Livestock Production (WCGALP), Vancouver, Canada, August 17-22, 2014, Paper 750.
  • Vinsky, M.D., Zhu, X., Zhang, X., and Li, C. (2014). "Functional analyses of multiple SNPs in the promoter regions of bovine genes.", Livestock Gentec 5th Annual conference, Edmonton, AB, Canada, August 12-14, 2014. (Poster)

2013

  • Ekine, C., Chen, L., Vinsky, M.D., Wang, Z., Stothard, P., Okine, E.K., Aldai, N., Dugan, M.E.R, McAllister, T.A., and Li, C. (2013). "Genetic influence of host animals on fatty acid composition in beef cattle tissues.", CSAS-CMSA Joint Annual Meeting, Banff Park Lodge Resort Hotel and Conference Centre, Banff, AB, Canada, June 18-20, 2013, O18-GS, pp. 10.
  • Vinsky, M.D., Zhu, X., Zhang, X., and Li, C. (2013). "Functional analyses of SNPs in the promoter regions of bovine genes.", CSAS-CMSA Joint Annual Meeting, Banff Park Lodge Resort Hotel and Conference Centre, Banff, AB, Canada, June 18-20, 2013. (Poster)

2011

  • Ekine, C., Aldai, N., Vinsky, M.D., Chen, L., Zeng, Z., Wang, Z., Stothard, P., Dugan, M.E.R, McAllister, T.A., and Li, C. (2011). "A multiple candidate-gene association approach to identifying single nucleotide polymorphisms (SNP) associated with fatty acid composition in commercial crossbred beef steers.", Livestock Gentec's 2nd Annual Conference: Addressing the Gap Between Discovery and Profitable Adoption, Edmonton, AB, Canada, October 19-20, 2011. (Poster)
  • Li, C., Vinsky, M.D., Ekine, C., Zeng, Z., Dugan, M.E.R, Aldai, N., and McAllister, T.A. (2011). "A multiple candidate gene association approach to identifying single nucleotide polymorphisms (SNP) associated with fatty acid composition in commercial crossbred beef steers.", Gordon Research Conferences on Quantitative Genetics and Genomics, Galveston, TX, USA, February 20-25, 2011. (Poster)
  • McLean, K.L., Dugan, M.E.R, McAllister, T.A., Basu, U., Li, C., He, M.L., Aalhus, J.L., Guan, L.L., and Fitzsimmons, C.J. (2011). "Identifying gene expression differences associated with a diet-induced increase of omega-3 fatty-acids in beef cattle.", Plant & Animal Genome XIX Conference, Town & Country Convention Center, San Diego, CA, USA, January 15-19, 2011, P708.

2010

  • Dugan, M.E.R and Li, C. (2010). "Identifying DNA markers for enhancing beneficial fatty acid in beef.", Future Fare, Alberta Livestock and Meat Agency (ALMA), Edmonton, AB, Canada, June 14, 2010. (Presentation)
  • Li, C., Aldai, N., Vinsky, M.D., Beaulieu, A.D., Patience, J.F., Dugan, M.E.R, Aalhus, J.L., McAllister, T.A. (2010). "A promoter SNP in bovine ACSF3 gene is associated with fatty acid composition in commercial crossbred steers.", Genomics and Livestock Quality Improvement Meeting, Calgary, AB, Canada, May 11-13, 2010. (Poster)
  • Li, C., Vinsky, M.D., Aldai, N., Osoro, K., and Dugan, M.E.R (2010). "Associations Of A Bovine SCD1 SNP With Fatty Acid Composition In Concentrate-Finished Yearling Bulls Of Different Muscular Hypertrophy Genotypes.", 9th World Congress on Genetics Applied to Livestock Production (WCGALP), Congress Center Leipzig (CCL), Leipzig, Germany, August 1-6, 2010, pp. 505.
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